Reactome | phospho-p-T200-CAMK4 [nucleoplasm]

phospho-p-T200-CAMK4 [nucleoplasm]

Stable Identifier

R-RNO-9619155

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

P13234

Locations in the PathwayBrowser

Expand all

Neuronal System (Rattus norvegicus)

- Transmission across Chemical Synapses (Rattus norvegicus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
    - Activation of NMDA receptors and postsynaptic events (Rattus norvegicus)
      - Post NMDA receptor activation events (Rattus norvegicus)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Rattus norvegicus)
        
        CAMK4 autophosphorylates (Rattus norvegicus)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Rattus norvegicus)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Intracellular signaling by second messengers (Rattus norvegicus)
  - DAG and IP3 signaling (Rattus norvegicus)
    - CaM pathway (Rattus norvegicus)
      - Calmodulin induced events (Rattus norvegicus)
        
        CaMK IV-mediated phosphorylation of CREB (Rattus norvegicus)
        
        CAMK4 autophosphorylates (Rattus norvegicus)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Rattus norvegicus)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Rattus norvegicus)
- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Opioid Signalling (Rattus norvegicus)
        
        G-protein mediated events (Rattus norvegicus)
        
        PLC beta mediated events (Rattus norvegicus)
        
        Ca-dependent events (Rattus norvegicus)
        
        CaM pathway (Rattus norvegicus)
        
        Calmodulin induced events (Rattus norvegicus)
        
        CaMK IV-mediated phosphorylation of CREB (Rattus norvegicus)
        
        CAMK4 autophosphorylates (Rattus norvegicus)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Rattus norvegicus)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P13234 Camk4

Gene Names

Camk4

Chain

chain:1-474

Reference Genes

BioGPS Gene:25050 Camk4

KEGG:rno:25050 Camk4

Monarch:25050 Camk4

NCBI Gene:25050 Camk4

UCSC:P13234 Camk4

Reference Transcript

RefSeq:NM_012727.3 Camk4

Other Identifiers

10800814

1369752_a_at

1369753_at

17722230

25050

5667901

5670542

5683831

5730403

5756724

5771201

5792482

5819535

5822428

5838554

6030762

6220660

6289165

6327001

6422705

6431802

6446991

6460056

6540237

6543828

6560886

6591402

6609157

A_44_P388650

GE1283713

GO:0000166

GO:0001650

GO:0002250

GO:0002376

GO:0003824

GO:0004672

GO:0004674

GO:0004683

GO:0005516

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005783

GO:0006355

GO:0006468

GO:0006954

GO:0007616

GO:0016301

GO:0016740

GO:0030154

GO:0043011

GO:0045893

GO:0050877

GO:0140096

ILMN_1349983

M63333exon_s_at

M74488cds_s_at

PH_rn_0004844

Participates

as a component of

p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Rattus norvegicus)

Other forms of this molecule

Camk4 [nucleoplasm]

p-T196-Camk4 [nucleoplasm]

Camk4 [nucleoplasm]

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm]

Inferred From

p-T200-CAMK4 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 200 (in Homo sapiens)

Coordinate

200

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_036859.2

ENSEMBL

ENSRNOT00000027771, ENSRNOG00000020478, ENSRNOP00000027771

IntEnz

2.7.11.17

PRO

P13234

GlyGen

P13234

RGD

2264