Formation of tri-heterotetramers of GluN1 (Grin1), GluN2A (Grin2a) and GluN2B (Grin2b)

Stable Identifier
R-RNO-9609964
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
Formation of tri-heterotetramers of GluN1 (Grin1), GluN2A (Grin2a) and GluN2B (Grin2b)

In rat brain, GluN1 (Grin1) forms a tri-heterotetramer with GluN2A (Grin2a) and GluN2B (Grin2b). The tetramer includes two molecules of GluN1, one molecule of GluN2A and one molecule of GluN2B (Sheng et al. 1994). The tetrameric structure was demonstrated for the Xenopus GluN1:GluN2A:GluN2B NMDA receptor (Lu et al. 2017).

Literature References
PubMed ID Title Journal Year
8139656 Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

Sheng, M, Cummings, J, Roldan, LA, Jan, YN, Jan, LY

Nature 1994
Participants
Orthologous Events
Authored
Reviewed
Created
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