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High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]
Stable Identifier
R-RNO-926774
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-2 family signaling (Rattus norvegicus)
Interleukin receptor SHC signaling (Rattus norvegicus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Rattus norvegicus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Rattus norvegicus)
Interleukin receptor SHC signaling (Rattus norvegicus)
Gab2 binds the p85 subunit of Class 1A PI3 kinases (Rattus norvegicus)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]
(Rattus norvegicus)
p85-containing Class 1A PI3Ks [cytosol]
(Rattus norvegicus)
Participates
as a member of
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Rattus norvegicus)
Inferred From
High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2:p85-containing Class 1A PI3Ks [plasma membrane]
(Homo sapiens)
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