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PEX12 [peroxisomal membrane]
Stable Identifier
R-RNO-8953911
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
peroxisomal membrane
Synonyms
O88177
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Protein ubiquitination (Rattus norvegicus)
E3 ubiquitin ligases ubiquitinate target proteins (Rattus norvegicus)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Rattus norvegicus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Rattus norvegicus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
Protein localization (Rattus norvegicus)
Class I peroxisomal membrane protein import (Rattus norvegicus)
PEX3:PEX19:class I PMP dissociates (Rattus norvegicus)
Class I Peroxisomal Membrane Proteins [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
Peroxisomal protein import (Rattus norvegicus)
Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Rattus norvegicus)
PEX5L:PEX7:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Rattus norvegicus)
PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Rattus norvegicus)
PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Rattus norvegicus)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Rattus norvegicus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Rattus norvegicus)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Rattus norvegicus)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Rattus norvegicus)
PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
PEX12 [peroxisomal membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:O88177
Reference Genes
BioGPS Gene:116718
ENSEMBL:ENSRNOG00000009718
ENSEMBL:ENSRNOG00000009718.5
ENSEMBL:ENSRNOG00055029462
ENSEMBL:ENSRNOG00060028884
ENSEMBL:ENSRNOG00065021081
KEGG Gene (Rattus norvegicus):116718
Monarch:116718
NCBI Gene:116718
Reference Transcript
RefSeq:NM_053921.1
RefSeq:XM_008773868.2
RefSeq:XM_003750890.4
RefSeq:XM_017596963.1
RefSeq:XM_008767934.2
RefSeq:XM_017602524.1
Other Identifiers
10745618
116718
1369070_at
17659339
5664037
5737961
5740331
5973821
6116789
6185879
6372303
6385851
6420154
6486574
AB002111_at
A_42_P561946
GE1276106
GE13016
GO:0005515
GO:0005777
GO:0005778
GO:0006886
GO:0007031
GO:0008270
GO:0016558
GO:0043226
GO:0055085
ILMN_1355019
PH_rn_0005046
Participates
as a member of
Class I Peroxisomal Membrane Proteins [peroxisomal membrane] (Rattus norvegicus)
as a component of
PEX2:PEX10:PEX12 [peroxisomal membrane] (Rattus norvegicus)
Other forms of this molecule
PEX12 [cytosol]
Inferred From
PEX12 [peroxisomal membrane]
(Homo sapiens)
Cross References
RefSeq
XP_003750938.1
,
XP_017452452.1
,
XP_017458013.1
,
XP_008772090.1
,
NP_446373.1
,
XP_008766156.1
Ensembl
ENSRNOP00000013233
,
ENSRNOG00000009718
,
ENSRNOT00000013233
PRO
O88177
RGD
620757
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