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PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane]
Stable Identifier
R-RNO-8868620
Type
Complex
Species
Rattus norvegicus
Compartment
clathrin-coated endocytic vesicle membrane
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
Clathrin-mediated endocytosis (Rattus norvegicus)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
RAB5 and GAPVD1 bind AP-2 (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
AAK1 [cytosol]
(Rattus norvegicus)
AMPH:BIN1 [cytosol]
(Rattus norvegicus)
ARP2/3 complex [cytosol]
(Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane]
(Rattus norvegicus)
DNM:GDP [cytosol]
(Rattus norvegicus)
Eps15 [cytosol]
(Rattus norvegicus)
f-actin [plasma membrane]
(Rattus norvegicus)
FNBP1 dimer [cytosol]
(Rattus norvegicus)
FNBP1L dimer [cytosol]
(Rattus norvegicus)
GAK,DNAJC6 [cytosol]
(Rattus norvegicus)
Ghost homologue of SGIP1 [cytosol]
(Rattus norvegicus)
Ghost homologue of WASL,CTTN [cytosol]
(Rattus norvegicus)
HIP1 dimer [cytosol]
(Rattus norvegicus)
HIP1R dimer [cytosol]
(Rattus norvegicus)
ITSNs [cytosol]
(Rattus norvegicus)
NECAPs [cytosol]
(Rattus norvegicus)
x 3
p-T156 AP-2 Complex [cytosol]
(Rattus norvegicus)
PACSIN dimers [cytosol]
(Rattus norvegicus)
PI4P [clathrin-coated endocytic vesicle membrane]
Reps1 [cytosol]
(Rattus norvegicus)
SH3GLs [cytosol]
(Rattus norvegicus)
SNX9,18 [cytosol]
(Rattus norvegicus)
SYNJs,OCRL [cytosol]
(Rattus norvegicus)
TRIP10 dimer [cytosol]
(Rattus norvegicus)
Participates
as an input of
RAB5 and GAPVD1 bind AP-2 (Rattus norvegicus)
as a component of
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
as an output of
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Rattus norvegicus)
Inferred From
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane]
(Homo sapiens)
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