Reactome | Snrpn [nucleoplasm]

Snrpn [nucleoplasm]

Stable Identifier

R-RNO-8865931

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

Me2-R108,R112-SNRPN, P63164

Locations in the PathwayBrowser

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Chromatin organization (Rattus norvegicus)

- ATP-dependent chromatin remodelers (Rattus norvegicus)
  - CHD chromatin remodelers (Rattus norvegicus)
    - CHD1 and CHD2 subfamily (Rattus norvegicus)
      - CHD1:H3K4me3 interacts with post-initiation transcription complexes (Rattus norvegicus)
        
        CHD1:H3K4 nucleosome:FACT complex:U2 snRNP complex:PAF1C complex [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)

Metabolism of RNA (Rattus norvegicus)

- Processing of Capped Intron-Containing Pre-mRNA (Rattus norvegicus)
  - mRNA 3'-end processing (Rattus norvegicus)
    - mRNA Polyadenylation (Rattus norvegicus)
      - CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - CPA complex components dissociate from polyadenylated pre-mRNA (intronic PAS) (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - CPA complex components dissociate from polyadenylated pre-mRNA (proximal 3'UTR PAS) (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - Core CPA complex binds capped pre-mRNA (Rattus norvegicus)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - PP1 dephosphorylates RNA Pol II (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - RBBP6 activates CPSF complex (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - Recruitment of other CPA components to pre-mRNA-bound CPA core (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
  - mRNA Splicing (Rattus norvegicus)
    - mRNA Splicing - Major Pathway (Rattus norvegicus)
      - Formation of the Spliceosomal B* complex (Rattus norvegicus)
        
        Spliceosomal B* complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal Bact complex [nucleoplasm] (Rattus norvegicus)
        
        U2 snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal C complex containing intron lariat (Rattus norvegicus)
        
        Spliceosomal B* complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal C complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal C* complex (Rattus norvegicus)
        
        Spliceosomal C complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal C* complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal P complex and exon ligation (Rattus norvegicus)
        
        Spliceosomal C* complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal P complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
      - Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Rattus norvegicus)
        
        Intron Lariat Spliceosome (ILS) [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal P complex [nucleoplasm] (Rattus norvegicus)
        
        U2 12S snRNP [nucleoplasm] (Rattus norvegicus)
        
        U2 Sm core complex [nucleoplasm] (Rattus norvegicus)
        
        Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)
        
        Snrpn [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P63164

Gene Names

Snrpn

Reference Genes

BioGPS Gene:81781 Snrpn

ENSEMBL:ENSRNOG00000054391

ENSEMBL:ENSRNOG00000059764

ENSEMBL:ENSRNOG00055015007

ENSEMBL:ENSRNOG00060000077

ENSEMBL:ENSRNOG00065003776

KEGG:rno:81781 Snrpn

Monarch:81781 Snrpn

NCBI Gene:81781 Snrpn

UCSC:P63164 Snrpn

Reference Transcript

RefSeq:NM_031117.2 Snrpn

Other Identifiers

10722489

1368098_a_at

17633623

5733259

5823123

5841673

5939849

6047349

6110293

6114639

6210592

6226304

6245094

6320680

6409679

6506756

6599616

6607746

6636195

6680668

6728807

6732037

81781

A_44_P157690

A_44_P238067

GE1230808

GE19683

GE21788

GO:0003723

ILMN_1365045

M29293_at

PH_rn_0004216

X73411mRNA_s_at

Participates

as a member of

Me2-R108,R112-SNRPB,SNRPN [nucleoplasm] (Rattus norvegicus)

Inferred From

Me2-R108,R112-SNRPN [nucleoplasm] (Homo sapiens)

Modified Residues

Name

symmetric dimethyl-L-arginine at 108 (in Homo sapiens)

Coordinate

108

PsiMod Name

symmetric dimethyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.

Name

symmetric dimethyl-L-arginine at 112 (in Homo sapiens)

Coordinate

112

PsiMod Name

symmetric dimethyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.

Cross References

RefSeq

NP_112379.1

ENSEMBL

ENSRNOP00000071994, ENSRNOT00000088874, ENSRNOG00000054391

PRO

P63164

RGD

621306

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