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IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]
Stable Identifier
R-RNO-873814
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Interferon Signaling (Rattus norvegicus)
Interferon gamma signaling (Rattus norvegicus)
Binding of STAT1 to p-IFNGR1 (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
STAT1 bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
IFNG signaling activates MAPKs (Rattus norvegicus)
Activated JAK1 binds RAF1 (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
JAK1-activated RAF1 phosphorylates MAPKs (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
JAK1-mediated phosphorylation of RAF1 (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
Phosphorylation of IFNGR1 by JAK kinases (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
Phosphorylation of STAT1 at Ser727 (Rattus norvegicus)
p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
Phosphorylation of STAT1 by JAK kinases (Rattus norvegicus)
STAT1 bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
Release of STAT1 dimer from active receptor unit (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
IFNG dimer [extracellular region]
(Rattus norvegicus)
p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane]
(Rattus norvegicus)
Participates
as a component of
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Rattus norvegicus)
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Rattus norvegicus)
STAT1 bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
as an output of
Release of STAT1 dimer from active receptor unit (Rattus norvegicus)
Phosphorylation of IFNGR1 by JAK kinases (Rattus norvegicus)
as an input of
Binding of STAT1 to p-IFNGR1 (Rattus norvegicus)
Inferred From
IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]
(Homo sapiens)
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