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80S ribosome [cytosol]
Stable Identifier
R-RNO-72500
Type
Complex
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Rattus norvegicus)
Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Translation (Rattus norvegicus)
Eukaryotic Translation Initiation (Rattus norvegicus)
Cap-dependent Translation Initiation (Rattus norvegicus)
Formation of a pool of free 40S subunits (Rattus norvegicus)
Release of 40S and 60S subunits from the 80S ribosome (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
GTP hydrolysis and joining of the 60S ribosomal subunit (Rattus norvegicus)
The 60S subunit joins the translation initiation complex (Rattus norvegicus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
eIF5B:GTP is hydrolyzed and released (Rattus norvegicus)
80S:Met-tRNAi:mRNA [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
Ribosome-associated quality control (Rattus norvegicus)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA (Rattus norvegicus)
ABCE1:ATP binds PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide and HBS1L-1:GDP is released (Rattus norvegicus)
ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Rattus norvegicus)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Rattus norvegicus)
ABCE1:ATP:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
PELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide (Rattus norvegicus)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Rattus norvegicus)
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA (Rattus norvegicus)
ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit (Rattus norvegicus)
ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Rattus norvegicus)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome (Rattus norvegicus)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
ZNF598:Ub:UBE2D1,2,3:80S Ribosome:mRNA:peptidyl-tRNA with nascent peptide [cytosol] (Rattus norvegicus)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
SRP-dependent cotranslational protein targeting to membrane (Rattus norvegicus)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Rattus norvegicus)
SRP:polypeptide+signal:ribosome [cytosol] (Rattus norvegicus)
ribosome:mRNA:polypeptide+signal [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
ribosome:mRNA:polypeptide+signal [cytosol] (Rattus norvegicus)
80S ribosome [cytosol] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
40S ribosomal complex [cytosol]
(Rattus norvegicus)
60S ribosomal complex [cytosol]
(Rattus norvegicus)
Participates
as a component of
80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
ribosome:mRNA:polypeptide+signal [cytosol] (Rattus norvegicus)
80S:Met-tRNAi:mRNA [cytosol] (Rattus norvegicus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Rattus norvegicus)
as an input of
Release of 40S and 60S subunits from the 80S ribosome (Rattus norvegicus)
Inferred From
80S ribosome [cytosol]
(Homo sapiens)
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