Reactome | Rpl36l3 [cytosol]

Rpl36l3 [cytosol]

Stable Identifier

R-RNO-72464

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

RPL36, D3ZZ95

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Rattus norvegicus)

- Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)
- rRNA processing (Rattus norvegicus)
  - rRNA processing in the nucleus and cytosol (Rattus norvegicus)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Rattus norvegicus)
      - 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Rattus norvegicus)
        
        60S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPL36 [cytosol] (Rattus norvegicus)
        
        Rpl36l3 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZZ95

Gene Names

Rpl36l3

Reference Genes

BioGPS Gene:100361060 Rpl36l3

ENSEMBL:ENSRNOG00000031947

ENSEMBL:ENSRNOG00000060478

ENSEMBL:ENSRNOG00000079261

KEGG:rno:100361060 Rpl36l3

Monarch:100361060 Rpl36l3

NCBI Gene:100361060 Rpl36l3

UCSC:D3ZZ95 Rpl36l3

Reference Transcript

RefSeq:XM_039101197.2 Rpl36l3

Other Identifiers

100361060

10710846

10747910

10760455

10806014

10820502

10890858

10931410

17620606

17869228

5633337

5759932

5803872

5805780

5827909

6077054

6080554

6188671

6254074

6273402

6391795

6406528

6447079

6451779

6478232

6605133

6638454

A_42_P789727

A_64_P129629

GO:0003735

GO:0005198

GO:0005840

GO:0006412

ILMN_1360804

rc_AA892123_at

Participates

as a member of

Homologues of RPL36 [cytosol] (Rattus norvegicus)

Inferred From

RPL36 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_038957125.1

ENSEMBL

ENSRNOP00000044605, ENSRNOT00000045531, ENSRNOG00000031947

RGD

2320900

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