Reactome | Rps20 [cytosol]

Rps20 [cytosol]

Stable Identifier

R-RNO-72349

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

RPS20, P60868

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Rattus norvegicus)

- Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)
- rRNA processing (Rattus norvegicus)
  - rRNA processing in the nucleus and cytosol (Rattus norvegicus)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Rattus norvegicus)
      - 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps20 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P60868

Gene Names

Rps20

Reference Genes

BioGPS Gene:122772 Rps20

ENSEMBL:ENSRNOG00000008555

ENSEMBL:ENSRNOG00000008555.8 Rps20

ENSEMBL:ENSRNOG00000029627

ENSEMBL:ENSRNOG00000029627.6 Rps20

ENSEMBL:ENSRNOG00000030345

ENSEMBL:ENSRNOG00000030345.5 Rps20

ENSEMBL:ENSRNOG00000071148

ENSEMBL:ENSRNOG00000071148.1 Rps20

ENSEMBL:ENSRNOG00055004879

ENSEMBL:ENSRNOG00055019075

ENSEMBL:ENSRNOG00055019740

ENSEMBL:ENSRNOG00055025102

ENSEMBL:ENSRNOG00060009945

ENSEMBL:ENSRNOG00060012450

ENSEMBL:ENSRNOG00060026202

ENSEMBL:ENSRNOG00060030657

ENSEMBL:ENSRNOG00065012867

ENSEMBL:ENSRNOG00065014371

ENSEMBL:ENSRNOG00065015526

ENSEMBL:ENSRNOG00065027926

ENSEMBL:ENSRNOG00065028011

KEGG Gene (Rattus norvegicus):100359951 Rps20

KEGG Gene (Rattus norvegicus):100362149 Rps20

KEGG Gene (Rattus norvegicus):100362684 Rps20

KEGG Gene (Rattus norvegicus):122772 Rps20

Monarch:122772 Rps20

NCBI Gene:122772 Rps20

UCSC:P60868 Rps20

Reference Transcript

Other Identifiers

10762140

10788666

10835975

10871337

10872531

10873786

10875267

10876420

10901251

10911999

10921288

122772

1371295_at

17803985

17805599

17856990

500451

5623294

5713670

5721192

5958874

5960370

5989093

6019399

6023544

6023562

6073491

6181385

6216584

6260360

6382447

6393613

6507201

6518958

6584334

6607980

6716867

A_44_P412277

GE16446

GO:0003723

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0015935

GO:0043226

GO:1990904

PH_rn_0024033

rc_AI012647_at

Participates

as a component of

40S ribosomal complex [cytosol] (Rattus norvegicus)

Other forms of this molecule

Rps20 [nucleoplasm]

Inferred From

RPS20 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_003753765.1, XP_002726693.1, XP_002730040.1, XP_002729204.1, XP_002729620.1, XP_002727194.1, NP_001007604.1

Ensembl

ENSRNOG00000071148, ENSRNOG00000008555, ENSRNOG00000029627, ENSRNOP00000011314, ENSRNOT00000011314, ENSRNOP00000065886, ENSRNOT00000040481, ENSRNOP00000066077, ENSRNOP00000069127, ENSRNOT00000051449, ENSRNOT00000041813, ENSRNOG00000030345

PRO

P60868

RGD

621037

PDB

7QVP, 7QGG

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