Reactome | Zc3h8 [nucleoplasm]

Zc3h8 [nucleoplasm]

Stable Identifier

R-RNO-6807406

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

ZC3H8, F7FCG9

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)
    - Integrator complex processes the 3' end of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
      - LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        LEC [nucleoplasm] (Rattus norvegicus)
        
        Zc3h8 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:F7FCG9

Gene Names

Zc3h8

Reference Genes

BioGPS Gene:311414 Zc3h8

ENSEMBL:ENSRNOG00000017647

Monarch:311414 Zc3h8

NCBI Gene:311414 Zc3h8

UCSC:F7FCG9 Zc3h8

Reference Transcript

Other Identifiers

10849813

1378119_at

1397886_at

17777155

311414

5676604

5709191

5734250

5754959

5793337

5831522

5878910

6309339

6341418

6354374

6377626

6424371

6520559

A_42_P497153

A_42_P733027

GE1187005

GO:0000122

GO:0000791

GO:0001162

GO:0001227

GO:0002376

GO:0003723

GO:0005634

GO:0005654

GO:0006351

GO:0006355

GO:0008023

GO:0008270

GO:0015030

GO:0016073

GO:0016604

GO:0033085

GO:0035363

GO:0042795

GO:0042796

GO:0043029

GO:0045892

GO:0045945

GO:0046677

GO:0046872

GO:0070245

ILMN_1376913

PH_rn_0006269

Participates

as a component of

LEC [nucleoplasm] (Rattus norvegicus)

Inferred From

ZC3H8 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001012090.1, XP_063139824.1

ENSEMBL

ENSRNOG00000017647, ENSRNOT00000023845, ENSRNOP00000023845

RGD

1310458

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