Reactome | PRKCA [cytosol]

PRKCA [cytosol]

Stable Identifier

R-RNO-58196

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

P05696

Locations in the PathwayBrowser

Expand all

Extracellular matrix organization (Rattus norvegicus)

- Non-integrin membrane-ECM interactions (Rattus norvegicus)
  - Syndecan interactions (Rattus norvegicus)
    - Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG (Rattus norvegicus)
      - Protein Kinase C, alpha type: DAG [plasma membrane] (Rattus norvegicus)
        
        PRKCA [cytosol] (Rattus norvegicus)
      - Syndecan-4:PI(4,5)P2:Protein kinase C, alpha type:DAG [plasma membrane] (Rattus norvegicus)
        
        Protein Kinase C, alpha type: DAG [plasma membrane] (Rattus norvegicus)
        
        PRKCA [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P05696

Reference Genes

BioGPS Gene:24680

ENSEMBL:ENSRNOG00000003491

ENSEMBL:ENSRNOG00055029138

ENSEMBL:ENSRNOG00060013871

ENSEMBL:ENSRNOG00065019003

KEGG:rno:24680

Monarch:24680

NCBI Gene:24680

UCSC:P05696

Reference Transcript

RefSeq:NM_001399299.2

Other Identifiers

10748473

1372176_at

1388825_at

17662664

24680

5646828

5673863

5735891

5755071

5787926

5808625

5861558

5867273

5906246

5995401

6006854

6012459

6021272

6025385

6037281

6127392

6200465

6306000

6352098

6423480

6492670

6494666

6603722

6633945

6719428

6735461

A_43_P19450

A_64_P019608

GE1182097

GE1227950

GE1229491

GE17956

GO:0000166

GO:0001525

GO:0001938

GO:0002159

GO:0003014

GO:0003824

GO:0004672

GO:0004674

GO:0004697

GO:0004698

GO:0005524

GO:0005634

GO:0005737

GO:0005739

GO:0005783

GO:0005815

GO:0005829

GO:0005886

GO:0006325

GO:0006338

GO:0006468

GO:0006915

GO:0007155

GO:0007611

GO:0008270

GO:0009967

GO:0010595

GO:0016020

GO:0016301

GO:0016740

GO:0017157

GO:0019899

GO:0023019

GO:0030163

GO:0030335

GO:0031666

GO:0031966

GO:0034330

GO:0034351

GO:0035403

GO:0036064

GO:0043161

GO:0043434

GO:0043491

GO:0043536

GO:0045766

GO:0045785

GO:0045931

GO:0046872

GO:0050877

GO:0051094

GO:0051240

GO:0070294

GO:0070528

GO:0070555

GO:0090330

GO:0106310

GO:0110063

GO:0140096

GO:1900016

ILMN_1372407

PH_rn_0011995

PH_rn_0022151

X07286cds_s_at

rc_AI073086_at

Participates

as a member of

as an input of

as a component of

Other forms of this molecule

PRKCA [nucleoplasm]

phospho-p-T497,T638,S657-PRKCA [nucleoplasm]

phospho-p-T497-PRKCA [cytosol]

PRKCA [plasma membrane]

phospho-p-T497,T638,S657-PRKCA [cytosol]

phospho-pT497,T638,S657-PRKCA [plasma membrane]

Inferred From

PRKCA [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001386228.1

ZINC - Investigational

KPCA_RAT

ENSEMBL

ENSRNOP00000004699, ENSRNOT00000004699, ENSRNOG00000003491

IntEnz

2.7.11.13

ZINC - Substances

KPCA_RAT

ZINC target

P05696

PRO

P05696

GlyGen

P05696

RGD

3395

ZINC - Predictions - Purchasable

KPCA_RAT

PDB

3GPE, 3RDJ, 2NCE, 1DSY, 5W4S, 4L1L, 3TWY

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P34901 Sdc4	20	Sdc4 [plasma membrane] (R-RNO-2076670) Sdc4 [plasma membrane] (R-RNO-2076633) Sdc4 [plasma membrane] (R-RNO-2076694) Sdc4 [plasma membrane] (R-RNO-2076653) Sdc4 [plasma membrane] (R-RNO-2076674) Sdc4 [plasma membrane] (R-RNO-2076635) Sdc4 [Golgi lumen] (R-RNO-2054111) Sdc4 [Golgi lumen] (R-RNO-2064195) Sdc4 [Golgi lumen] (R-RNO-2064249) Sdc4 [Golgi lumen] (R-RNO-2064100) Sdc4 [Golgi lumen] (R-RNO-2064067) Sdc4 [Golgi lumen] (R-RNO-2076374) Sdc4 [Golgi lumen] (R-RNO-2076394) Sdc4 [Golgi lumen] (R-RNO-2076446) Sdc4 [Golgi lumen] (R-RNO-2076460) Sdc4 [Golgi lumen] (R-RNO-2076613) Sdc4 [Golgi lumen] (R-RNO-2076434) Sdc4 [Golgi lumen] (R-RNO-2076411) Sdc4 [Golgi lumen] (R-RNO-2076418) Sdc4 [Golgi lumen] (R-RNO-2076407)	0.499	3