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p-2S MAP2K homo/heterodimers [cytosol]
Stable Identifier
R-RNO-5672721
Type
Set [DefinedSet]
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
MAP2K and MAPK activation (Rattus norvegicus)
Dissociation of RAS:RAF complex (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
Dual mechanism MAPK inhibitors bind MAPKs (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
IL17RD binds p-2S MAP2Ks and MAPKs (Rattus norvegicus)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Rattus norvegicus)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Rattus norvegicus)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
MAP2Ks phosphorylate MAPKs (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
RAF phosphorylates MAP2K dimer (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
RAF activation (Rattus norvegicus)
Phosphorylation of RAF (Rattus norvegicus)
RAF activating kinases [plasma membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
Signalling to ERKs (Rattus norvegicus)
Prolonged ERK activation events (Rattus norvegicus)
Frs2-mediated activation (Rattus norvegicus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Rattus norvegicus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
Dissociation of phosphorylated MAP2Ks and MAPKs (Rattus norvegicus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Rattus norvegicus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Rattus norvegicus)
p-2S MAP2K homo/heterodimers [cytosol] (Rattus norvegicus)
Participants
members
p-2S MAP2K1:p-2S MAPK2K2 heterodimer [cytosol]
(Rattus norvegicus)
p-S218,S222 MAP2K1 dimer [cytosol]
(Rattus norvegicus)
p-S222,S226 MAP2K2 dimer [cytosol]
(Rattus norvegicus)
Participates
as a component of
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Rattus norvegicus)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Rattus norvegicus)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Rattus norvegicus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Rattus norvegicus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
as an input of
IL17RD binds p-2S MAP2Ks and MAPKs (Rattus norvegicus)
as an output of
Dissociation of phosphorylated MAP2Ks and MAPKs (Rattus norvegicus)
Dissociation of RAS:RAF complex (Rattus norvegicus)
as a candidate of
RAF activating kinases [plasma membrane] (Rattus norvegicus)
Inferred From
p-2S MAP2K homo/heterodimers [cytosol]
(Homo sapiens)
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