Reactome | RAS GEFs [plasma membrane]

RAS GEFs [plasma membrane]

Stable Identifier

R-RNO-5672601

Type

Set [DefinedSet]

Species

Rattus norvegicus

Compartment

cytosol, plasma membrane

Locations in the PathwayBrowser

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Participants

members

Activated FGFR1:p-FRS2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR2:p-FRS:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR2:pY-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR3:p-FRS:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR3:pY-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR4:p-FRS2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR4:pY-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Grb2:Sos:pFAK bound to NCAM1:pFyn [plasma membrane] (Rattus norvegicus)
NRGs/EGFLs:p-ERBB4:p-ERBB2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Rattus norvegicus)
GRB2:SOS1:p-Y349,350-SHC1:p-ERBB4 [plasma membrane] (Rattus norvegicus)
EGF:p-EGFR:p-ERBB2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 [cytosol] (Rattus norvegicus)
GRB2-1:SOS1:p-Y427-SHC1 [cytosol] (Rattus norvegicus)
p-5Y-LAT:p-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y349,350-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
GRB2:SOS1:HB-EGF:p-6Y-EGFR [plasma membrane] (Rattus norvegicus)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Rattus norvegicus)
SOS-1 bound to Tie2:Grb2 [plasma membrane] (Rattus norvegicus)
p-RASGRP1,3:DAG [plasma membrane] (Rattus norvegicus)
GRB2:SOS1:p-KIT complex [plasma membrane] (Rattus norvegicus)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
GRB2-1:SOS1:p-Y-SHC [cytosol] (Rattus norvegicus)
RAPGEF2 [cytosol] (Rattus norvegicus)
Rasgef1a [cytosol] (Rattus norvegicus)
Rasgrf2 [cytosol] (Rattus norvegicus)
RASGRP1 [cytosol] (Rattus norvegicus)
Rasgrp4 [cytosol] (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
Active FLT3:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)

Inferred From

RAS GEFs [plasma membrane] (Homo sapiens)

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