Reactome | NrCAM binds Ankyrin-G

NrCAM binds Ankyrin-G

Stable Identifier

R-RNO-447024

Type

Reaction [binding]

Species

Rattus norvegicus

Compartment

cytosol, plasma membrane

ReviewStatus

5/5

General

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SVG | | PPTX | SBGN

NrCAM is expressed specifically at node of ranvier where it interacts with the cytoskeletal adaptor protein ankyrin-G with the conserved motif F1272IGQY.

Literature References

PubMed ID	Title	Journal	Year
9278538	Morphogenesis of the node of Ranvier: co-clusters of ankyrin and ankyrin-binding integral proteins define early developmental intermediates Bennett, V, Lambert, S, Davis, JQ	J Neurosci	1997
11449000	Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation Kirsch, FP, Rathjen, FG, Moré, MI	J Cell Biol	2001