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SIRT1 [nucleoplasm]
Stable Identifier
R-RNO-427531
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
A0A0G2JZ79
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Rattus norvegicus)
Cell junction organization (Rattus norvegicus)
Cell-cell junction organization (Rattus norvegicus)
Adherens junctions interactions (Rattus norvegicus)
Regulation of Homotypic Cell-Cell Adhesion (Rattus norvegicus)
Regulation of Expression and Function of Type I Classical Cadherins (Rattus norvegicus)
Regulation of CDH1 Expression and Function (Rattus norvegicus)
Regulation of CDH1 Gene Transcription (Rattus norvegicus)
Negative Regulation of CDH1 Gene Transcription (Rattus norvegicus)
ZEB1 recruits MPHOSPH8 (MPP8) to CDH1 gene promoter (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
SIRT1:MPHOSPH8:ZEB1:CDH1 gene [nucleoplasm] (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to heat stress (Rattus norvegicus)
Regulation of HSF1-mediated heat shock response (Rattus norvegicus)
SIRT1 binds to HSF1 (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
SIRT1 deacetylates HSF1 (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
Developmental Biology (Rattus norvegicus)
MITF-M-regulated melanocyte development (Rattus norvegicus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Rattus norvegicus)
HINT1 binds MITF-M (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
SIRT1 deacetylates HINT1 dimer (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
Epigenetic regulation of gene expression (Rattus norvegicus)
Epigenetic regulation by WDR5-containing histone modifying complexes (Rattus norvegicus)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Rattus norvegicus)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Rattus norvegicus)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Rattus norvegicus)
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
Negative epigenetic regulation of rRNA expression (Rattus norvegicus)
SIRT1 negatively regulates rRNA expression (Rattus norvegicus)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
eNoSC [nucleoplasm] (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
eNoSC deacetylates histone H3 (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
eNoSC [nucleoplasm] (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
eNoSC dimethylates histone H3 at lysine-9 (Rattus norvegicus)
eNoSC [nucleoplasm] (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
FOXO-mediated transcription (Rattus norvegicus)
Regulation of FOXO transcriptional activity by acetylation (Rattus norvegicus)
SIRT1,SIRT3 deacetylate FOXO3 (Rattus norvegicus)
SIRT1,SIRT3 [nucleoplasm] (Rattus norvegicus)
SIRT1 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A0G2JZ79
Reference Genes
BioGPS Gene:309757
ENSEMBL:ENSRNOG00000051592
ENSEMBL:ENSRNOG00055009872
ENSEMBL:ENSRNOG00060002890
ENSEMBL:ENSRNOG00065022979
Monarch:309757
NCBI Gene:309757
UCSC:A0A0G2JZ79
Reference Transcript
RefSeq:NM_001414959.1
Participates
as an input of
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Rattus norvegicus)
SIRT1 binds to HSF1 (Rattus norvegicus)
ZEB1 recruits MPHOSPH8 (MPP8) to CDH1 gene promoter (Rattus norvegicus)
as a component of
eNoSC [nucleoplasm] (Rattus norvegicus)
SIRT1:HSP70:DNAJB1:Ac-K80-HSF1:target gene [nucleoplasm] (Rattus norvegicus)
SIRT1:MPHOSPH8:ZEB1:CDH1 gene [nucleoplasm] (Rattus norvegicus)
as an output of
SIRT1 deacetylates HSF1 (Rattus norvegicus)
as a member of
SIRT1,SIRT3 [nucleoplasm] (Rattus norvegicus)
This entity regulates
Positively
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci
(Rattus norvegicus)
HINT1 binds MITF-M
(Rattus norvegicus)
Inferred From
SIRT1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001401888.1
PRO
A0A0G2JZ79
RGD
1308542
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