NCAM1 cis-homophilic interaction

Stable Identifier
R-RNO-420387
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NCAM1 cis-homophilic interaction
NCAM1 located on the cell membrane can participate in parallel cis and antiparallel trans-homophilic interactions. The cis-interaction is mediated by reciprocal IgI-IgII interactions: the IgI domain of one NCAM1 molecule interacts with the IgII domain of a second.
Literature References
PubMed ID Title Journal Year
14527396 Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion

Soroka, V, Kolkova, K, Kastrup, JS, Diederichs, K, Breed, J, Kiselyov, VV, Poulsen, FM, Larsen, IK, Welte, W, Berezin, V, Bock, E, Kasper, C

Structure 2003
Participants
Input
Output
Orthologous Events
NCAM1 cis-homophilic interaction (Homo sapiens)
Authored
Garapati, P V  (2009-02-24)
Reviewed
Maness, PF  (2009-05-26)
Walmod, PS  (2009-05-26)
Created
Garapati, P V  (2009-05-11)
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