Reactome | P2RY1 [plasma membrane]

P2RY1 [plasma membrane]

Stable Identifier

R-RNO-391956

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P49651

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (q) signalling events (Rattus norvegicus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        P2RY1:ADP [plasma membrane] (Rattus norvegicus)
        
        P2RY1 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        P2RY1:ADP [plasma membrane] (Rattus norvegicus)
        
        P2RY1 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Nucleotide-like (purinergic) receptors (Rattus norvegicus)
        
        P2Y receptors (Rattus norvegicus)
        
        P2RY1 binds ADP (Rattus norvegicus)
        
        P2RY1 [plasma membrane] (Rattus norvegicus)
        
        P2RY1:ADP [plasma membrane] (Rattus norvegicus)
        
        P2RY1 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P49651

Reference Genes

BioGPS Gene:25265

ENSEMBL:ENSRNOG00000014232

ENSEMBL:ENSRNOG00000014232.5

ENSEMBL:ENSRNOG00055018671

ENSEMBL:ENSRNOG00060005357

ENSEMBL:ENSRNOG00065026099

KEGG Gene (Rattus norvegicus):25265

Monarch:25265

NCBI Gene:25265

UCSC:P49651

Reference Transcript

RefSeq:NM_012800.1

Other Identifiers

10815652

1370606_at

17738812

25265

5747066

5755834

5847017

5933309

6502229

6559849

6654164

A_64_P069051

GE1100884

GO:0001621

GO:0003012

GO:0004930

GO:0005524

GO:0005886

GO:0005929

GO:0006811

GO:0007186

GO:0007200

GO:0008360

GO:0016020

GO:0023052

GO:0030168

GO:0042060

GO:0043226

GO:0043270

GO:0045028

GO:0048856

GO:0051649

GO:0060089

GO:0071407

GO:0071415

GO:0090075

U22830_at

Participates

as an input of

P2RY1 binds ADP (Rattus norvegicus)

as a component of

P2RY1:ADP [plasma membrane] (Rattus norvegicus)

Inferred From

P2RY1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_036932.1

ZINC - Metabolites

P2RY1_RAT

ZINC - World Drugs

P2RY1_RAT

ZINC - Substances

P2RY1_RAT

ZINC - Biogenic

P2RY1_RAT

Ensembl

ENSRNOP00000019304, ENSRNOT00000019305, ENSRNOG00000014232

ZINC target

P49651

PRO

P49651

RGD

3242

ZINC - Predictions - Purchasable

P2RY1_RAT

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25099	1	Adora1 [plasma membrane] (R-RNO-418941)	0.471	2