Reactome | ADCY7 [plasma membrane]

ADCY7 [plasma membrane]

Stable Identifier

R-RNO-379057

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

F1LQT1

Locations in the PathwayBrowser

Expand all

Neuronal System (Rattus norvegicus)

- Transmission across Chemical Synapses (Rattus norvegicus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
    - GABA receptor activation (Rattus norvegicus)
      - GABA B receptor activation (Rattus norvegicus)
        
        Activation of GABAB receptors (Rattus norvegicus)
        
        Adenylate cyclase inhibitory pathway (Rattus norvegicus)
        
        Adenylate cyclase increases the GTPase activity of G alpha-olf (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase increases the GTPase activity of Gi alpha (Rattus norvegicus)
        
        (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Dissociation of the Gi alpha:G olf complex (Rattus norvegicus)
        
        (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Intracellular signaling by second messengers (Rattus norvegicus)
  - DAG and IP3 signaling (Rattus norvegicus)
    - CaM pathway (Rattus norvegicus)
      - Calmodulin induced events (Rattus norvegicus)
        
        PKA-mediated phosphorylation of CREB (Rattus norvegicus)
        
        PKA activation (Rattus norvegicus)
        
        Adenylate cyclase produces cAMP (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Opioid Signalling (Rattus norvegicus)
        
        G-protein mediated events (Rattus norvegicus)
        
        Adenylate cyclase activating pathway (Rattus norvegicus)
        
        Adenylate cyclase converts ATP into cyclic AMP (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Adenylaye cyclase increases the GTPase activity of G alpha-olf (Rattus norvegicus)
        
        G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Galpha-olf:GTP binds to adenylate cyclase and activates it (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase inhibitory pathway (Rattus norvegicus)
        
        Adenylate cyclase increases the GTPase activity of G alpha-olf (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase increases the GTPase activity of Gi alpha (Rattus norvegicus)
        
        (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Dissociation of the Gi alpha:G olf complex (Rattus norvegicus)
        
        (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Rattus norvegicus)
        
        (Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        PLC beta mediated events (Rattus norvegicus)
        
        Ca-dependent events (Rattus norvegicus)
        
        CaM pathway (Rattus norvegicus)
        
        Calmodulin induced events (Rattus norvegicus)
        
        PKA-mediated phosphorylation of CREB (Rattus norvegicus)
        
        PKA activation (Rattus norvegicus)
        
        Adenylate cyclase produces cAMP (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
    - G alpha (z) signalling events (Rattus norvegicus)
      - G alpha (z) inhibits adenylate cyclase (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
        
        G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Rattus norvegicus)
        
        Adenylate cyclase [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)
- Signaling by Hedgehog (Rattus norvegicus)
  - Hedgehog 'off' state (Rattus norvegicus)
    - GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Rattus norvegicus)
      - adenylate cyclases:Mg2+ [plasma membrane] (Rattus norvegicus)
        
        adenylate cyclases [plasma membrane] (Rattus norvegicus)
        
        ADCY7 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:F1LQT1

Reference Genes

BioGPS Gene:84420

ENSEMBL:ENSRNOG00000014776

KEGG:rno:84420

Monarch:84420

NCBI Gene:84420

UCSC:F1LQT1

Reference Transcript

Other Identifiers

10809688

1379598_at

17732070

5697057

5741682

5970164

6016539

6097399

6097654

6148561

6200646

6217912

6222854

6271111

6282759

6340499

6373394

6414421

6452410

6556224

6559331

6560642

6565177

6567345

6596201

6647158

6647223

6671846

6686479

6732258

6737524

84420

A_44_P494183

A_64_P083913

A_64_P083918

GE1215923

GO:0002819

GO:0003824

GO:0004016

GO:0005886

GO:0006171

GO:0009190

GO:0009975

GO:0016020

GO:0016829

GO:0016849

GO:0035556

GO:0055086

GO:0071285

GO:0071361

GO:1900016

GO:1901135

ILMN_1373467

PH_rn_0011755

PH_rn_0020672

rc_AA894292_at

Participates

as a candidate of

adenylate cyclases [plasma membrane] (Rattus norvegicus)

as a member of

Adenylate cyclase [plasma membrane] (Rattus norvegicus)

Inferred From

ADCY7 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_017456880.1, XP_017456877.1, XP_017456879.1, XP_017456881.1, XP_017456882.1, XP_017456871.1, XP_017456870.1, XP_063134393.1, NP_445848.1, XP_017456872.1, XP_017456873.1

ENSEMBL

ENSRNOP00000020700, ENSRNOT00000020700, ENSRNOG00000014776

RGD

619966

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