Reactome | Sumo1 [nucleoplasm]

Sumo1 [nucleoplasm]

Stable Identifier

R-RNO-3730622

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

UBE2I-G97-SUMO1, Q5I0H3

Locations in the PathwayBrowser

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DNA Repair (Rattus norvegicus)

- DNA Double-Strand Break Repair (Rattus norvegicus)
  - DNA Double Strand Break Response (Rattus norvegicus)
    - Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Rattus norvegicus)
      - PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Rattus norvegicus)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Rattus norvegicus)
        
        Sumo1 [nucleoplasm] (Rattus norvegicus)
- Nucleotide Excision Repair (Rattus norvegicus)
  - Global Genome Nucleotide Excision Repair (GG-NER) (Rattus norvegicus)
    - Formation of Incision Complex in GG-NER (Rattus norvegicus)
      - SUMOylation of XPC (Rattus norvegicus)
        
        SUMO1,2,3:UBE2I [nucleoplasm] (Rattus norvegicus)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Rattus norvegicus)
        
        Sumo1 [nucleoplasm] (Rattus norvegicus)

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - Generic Transcription Pathway (Rattus norvegicus)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Rattus norvegicus)
      - Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Rattus norvegicus)
        
        SUMOylation of TFAP2C with SUMO1 (Rattus norvegicus)
        
        SUMO1:C93-UBE2I [nucleoplasm] (Rattus norvegicus)
        
        Sumo1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q5I0H3

Gene Names

Sumo1

Reference Genes

BioGPS Gene:301442 Sumo1

ENSEMBL:ENSRNOG00000016133

ENSEMBL:ENSRNOG00055023851

ENSEMBL:ENSRNOG00060019006

ENSEMBL:ENSRNOG00065027194

KEGG:rno:301442 Sumo1

Monarch:301442 Sumo1

NCBI Gene:301442 Sumo1

UCSC:Q5I0H3 Sumo1

Reference Transcript

RefSeq:NM_001009672.1 Sumo1

Other Identifiers

10928423

1399095_at

17864932

301442

5657700

5708775

5729733

5766522

5876828

6017013

6555545

6579011

6584808

6679680

AA686579_at

A_44_P253858

A_64_P135903

GE1188977

GO:0005515

ILMN_1362579

PH_rn_0015014

rc_AA850550_at

Participates

as a component of

SUMO1:C93-UBE2I [nucleoplasm] (Rattus norvegicus)

Other forms of this molecule

Sumo1 [cytosol]

Sumo1 [nucleoplasm]

Inferred From

UBE2I-G97-SUMO1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

Inter-chain Crosslink via S-(glycyl)-L-cysteine (Cys-Gly) at 97 and 93 (in Homo sapiens)

Coordinate

PsiMod Name

S-(glycyl)-L-cysteine (Cys-Gly)

PsiMod Definition

A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.

Cross References

RefSeq

NP_001009672.1

ENSEMBL

ENSRNOG00000016133, ENSRNOT00000022047, ENSRNOP00000022048

PRO

Q5I0H3

RGD

1306919

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42260	2	GRIK2 [plasma membrane] (R-RNO-450192) Edited GRIK2 (GluR6) [plasma membrane] (R-RNO-451318)	0.702	4
UniProt:P38656 LA			0.524	3
UniProt:P20272	1	Cnr1 [plasma membrane] (R-RNO-419411)	0.463	2

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