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Slc18a3 [plasma membrane]
Stable Identifier
R-RNO-372513
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
SLC18A3, Q62666
Locations in the PathwayBrowser
Expand all
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter release cycle (Rattus norvegicus)
Acetylcholine Neurotransmitter Release Cycle (Rattus norvegicus)
Release of acetylcholine at the synapse (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
Clathrin-mediated endocytosis (Rattus norvegicus)
BAR domain proteins recruit dynamin (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
Cargo recognition for clathrin-mediated endocytosis (Rattus norvegicus)
AP-2 directly binds some endocytic cargo (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
Clathrin recruits PIK3C2A (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
F- and N- BAR domain proteins bind the clathrin-coated pit (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
SNX9 recruits components of the actin polymerizing machinery (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 cargo [plasma membrane] (Rattus norvegicus)
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
Slc18a3 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q62666
Gene Names
Slc18a3
Reference Genes
BioGPS Gene:60422 Slc18a3
ENSEMBL:ENSRNOG00000062141
KEGG Gene (Rattus norvegicus):60422 Slc18a3
Monarch:60422 Slc18a3
NCBI Gene:60422 Slc18a3
UCSC:Q62666 Slc18a3
Reference Transcript
RefSeq:NM_031663.2 Slc18a3
Participates
as a member of
AP-2 YXXPhi cargo [plasma membrane] (Rattus norvegicus)
as an output of
Release of acetylcholine at the synapse (Rattus norvegicus)
Other forms of this molecule
Slc18a3 [clathrin-coated endocytic vesicle membrane]
Slc18a3 [clathrin-sculpted acetylcholine transport vesicle membrane]
Inferred From
SLC18A3 [plasma membrane]
(Homo sapiens)
Cross References
ZINC - Investigational
VACHT_RAT
RefSeq
NP_113851.1
ZINC - Substances
VACHT_RAT
ZINC target
Q62666
PRO
Q62666
ZINC - Predictions - Purchasable
VACHT_RAT
RGD
62072
GlyGen
Q62666
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