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About
What is Reactome ?
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Team
Scientific Advisory Board
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Release Calendar
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License Agreement
Privacy Notice
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Digital Preservation
Contact us
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Table of Contents
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TNF-α trimer:TNF-R1 trimer [plasma membrane]
Stable Identifier
R-RNO-3371401
Type
Set [DefinedSet]
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
TNF signaling (Rattus norvegicus)
Regulation of TNFR1 signaling (Rattus norvegicus)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
K63polyUb-RIPK1 is deubiquitinated (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
LUBAC ubiquitinates RIPK1 at K627 (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
OPTN binds polyUb-RIPK1 within the TNFR1 complex (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
OPTN recruits CYLD to the TNFR1 complex (Rattus norvegicus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1 binds DENN/MADD (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:DENN-SV,MADD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Rattus norvegicus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Rattus norvegicus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TRAF1 binds TRAF2 within TNFR1 signaling complex (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFR1-induced NF-kappa-B signaling pathway (Rattus norvegicus)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:CHUK:IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFR1-induced proapoptotic signaling (Rattus norvegicus)
TRADD:TRAF2:RIP1 complex dissociates from the TNF-α:TNF-R1 complex. (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNFR1-mediated ceramide production (Rattus norvegicus)
TNF-α:TNFR1 binds NSMAF (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF binds GNB2L1 (Rattus norvegicus)
TNF-α:TNFR1:NSMAF [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF:GNB2L1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Rattus norvegicus)
TNF-alpha:TNFR1:NSMAF:GNB2L1:SMPD2,3 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF:GNB2L1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF:GNB2L1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:NSMAF [plasma membrane] (Rattus norvegicus)
TNF-α trimer:TNF-R1 trimer [plasma membrane] (Rattus norvegicus)
Participants
members
TNF-α:TNFR1 [plasma membrane]
(Rattus norvegicus)
soluble TNF-α:TNFR1 [plasma membrane]
(Rattus norvegicus)
Participates
as an input of
TNF-α:TNFR1 binds NSMAF (Rattus norvegicus)
TRAF1 binds TRAF2 within TNFR1 signaling complex (Rattus norvegicus)
TNF-α:TNFR1 binds DENN/MADD (Rattus norvegicus)
TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Rattus norvegicus)
as a component of
TNF-α:TNFR1:NSMAF [plasma membrane] (Rattus norvegicus)
TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Rattus norvegicus)
TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:DENN-SV,MADD [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Rattus norvegicus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Rattus norvegicus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2 [plasma membrane] (Rattus norvegicus)
as an output of
TRADD:TRAF2:RIP1 complex dissociates from the TNF-α:TNF-R1 complex. (Rattus norvegicus)
Inferred From
TNF-α trimer:TNF-R1 trimer [plasma membrane]
(Homo sapiens)
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