Reactome | Wipf3 [cytosol]

Wipf3 [cytosol]

Stable Identifier

R-RNO-2197670

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

WIPF3, Q9Z0G8

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Innate Immune System (Rattus norvegicus)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
    - Regulation of actin dynamics for phagocytic cup formation (Rattus norvegicus)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
      - Detachment of WASP/WAVE (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
      - Src phosphorylate WASP,N-WASP (Rattus norvegicus)
        
        CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
  - Signaling by Rho GTPases (Rattus norvegicus)
    - RHO GTPase Effectors (Rattus norvegicus)
      - RHO GTPases Activate WASPs and WAVEs (Rattus norvegicus)
        
        (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        Detachment of WASP/WAVE (Rattus norvegicus)
        
        Mother filament:branching complex [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        Src phosphorylate WASP,N-WASP (Rattus norvegicus)
        
        CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Rattus norvegicus)
        
        WIP family proteins [cytosol] (Rattus norvegicus)
        
        Wipf3 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q9Z0G8

Gene Names

Wipf3

Reference Genes

BioGPS Gene:259242 Wipf3

ENSEMBL:ENSRNOG00000009571

ENSEMBL:ENSRNOG00055010789

ENSEMBL:ENSRNOG00060029915

KEGG:rno:259242 Wipf3

Monarch:259242 Wipf3

NCBI Gene:259242 Wipf3

UCSC:Q9Z0G8 Wipf3

Reference Transcript

Other Identifiers

10855637

1370596_a_at

1370648_a_at

17783679

259242

5629294

5731994

5765439

5784580

5896954

6002829

6050705

6093820

6177906

6296514

6318800

6429057

6524783

6528115

6669061

6707692

6734987

A_44_P110726

A_44_P174181

A_64_P163416

GE20895

GO:0003779

GO:0005768

GO:0005769

GO:0008092

GO:0034314

GO:0043014

GO:0071203

ILMN_1360553

PH_rn_0003163

PH_rn_0019400

U25281_at

U31159_s_at

U31160mRNA_s_at

Participates

as a member of

WIP family proteins [cytosol] (Rattus norvegicus)

Inferred From

WIPF3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001385659.1, NP_671744.1

ENSEMBL

ENSRNOG00000009571, ENSRNOP00000012755, ENSRNOT00000012755

PRO

Q9Z0G8

RGD

708559

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