Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Zfyve9 [early endosome membrane]
Stable Identifier
R-RNO-206180
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
early endosome membrane
Synonyms
ZFYVE9-1, D3ZDC7
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by TGFB family members (Rattus norvegicus)
Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
TGF-beta receptor signaling activates SMADs (Rattus norvegicus)
Activated type I receptor phosphorylates SMAD2/3 directly (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Rattus norvegicus)
Zfyve9 [early endosome membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Rattus norvegicus)
Zfyve9 [early endosome membrane] (Rattus norvegicus)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Rattus norvegicus)
Zfyve9 [early endosome membrane] (Rattus norvegicus)
Zfyve9 [early endosome membrane] (Rattus norvegicus)
Phosphorylated SMAD2/3 dissociates from TGFBR (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Rattus norvegicus)
Zfyve9 [early endosome membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Rattus norvegicus)
Zfyve9 [early endosome membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZDC7
Gene Names
Zfyve9
Reference Genes
BioGPS Gene:313477 Zfyve9
ENSEMBL:ENSRNOG00000027183
KEGG:rno:313477 Zfyve9
Monarch:313477 Zfyve9
NCBI Gene:313477 Zfyve9
UCSC:D3ZDC7 Zfyve9
Reference Transcript
RefSeq:XM_063287711.1 Zfyve9
RefSeq:XM_039109963.2 Zfyve9
RefSeq:NM_001107952.1 Zfyve9
Other Identifiers
10878653
1381049_at
1391285_at
17809258
313477
5728446
5746934
5774367
5802008
5900842
5972007
5976781
6001364
6003962
6016022
6208565
6216292
6242046
6344099
6366634
6391780
6411680
6426004
6434893
6444414
6474445
6605163
6620758
6648714
6676320
A_44_P1048487
A_44_P239105
GE1199473
GE1250427
GO:0005545
GO:0005829
GO:0007179
GO:0019904
GO:0031901
GO:0032991
GO:0046872
ILMN_1358649
PH_rn_0012200
rc_AI029694_at
rc_AI112685_at
Participates
as an input of
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Rattus norvegicus)
as a component of
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane] (Rattus norvegicus)
TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane] (Rattus norvegicus)
Inferred From
ZFYVE9-1 [early endosome membrane]
(Homo sapiens)
Cross References
RefSeq
XP_063143781.1
,
NP_001101422.1
,
XP_038965891.1
ENSEMBL
ENSRNOP00000036295
,
ENSRNOT00000037523
,
ENSRNOG00000027183
RGD
1310856
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text