Reactome | Rictor [cytosol]

Rictor [cytosol]

Stable Identifier

R-RNO-198632

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

RICTOR, A0A8I5ZNG4

Locations in the PathwayBrowser

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Cellular responses to stimuli (Rattus norvegicus)

- Cellular responses to mechanical stimuli (Rattus norvegicus)
  - Response of endothelial cells to shear stress (Rattus norvegicus)
    - High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Rattus norvegicus)
      - mTORC2 phosphorylates AKT1 on serine-473 (Rattus norvegicus)
        
        mTORC2:PIP3 [plasma membrane] (Rattus norvegicus)
        
        Rictor [cytosol] (Rattus norvegicus)

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - Generic Transcription Pathway (Rattus norvegicus)
    - Transcriptional Regulation by TP53 (Rattus norvegicus)
      - Regulation of TP53 Activity (Rattus norvegicus)
        
        Regulation of TP53 Expression and Degradation (Rattus norvegicus)
        
        Regulation of TP53 Degradation (Rattus norvegicus)
        
        mTORC2 phosphorylates SGK1 (Rattus norvegicus)
        
        mTORC2:PIP3 [plasma membrane] (Rattus norvegicus)
        
        Rictor [cytosol] (Rattus norvegicus)

Immune System (Rattus norvegicus)

- Adaptive Immune System (Rattus norvegicus)
  - Regulation of T cell activation by CD28 family (Rattus norvegicus)
    - Co-stimulation by CD28 (Rattus norvegicus)
      - CD28 dependent PI3K/Akt signaling (Rattus norvegicus)
        
        mTORC2 phosphorylates AKT at S473 (Rattus norvegicus)
        
        mTORC2:PIP3 [plasma membrane] (Rattus norvegicus)
        
        Rictor [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5ZNG4

Gene Names

Rictor

Reference Genes

BioGPS Gene:310131 Rictor

ENSEMBL:ENSRNOG00000011341

Monarch:310131 Rictor

NCBI Gene:310131 Rictor

UCSC:A0A8I5ZNG4 Rictor

Reference Transcript

RefSeq:XM_039103527.1 Rictor

Other Identifiers

10813407

1372197_at

1397877_at

17736195

310131

5617853

5630141

5637087

5641774

5686616

5694653

5700809

5737500

5756198

5782158

5788543

5795335

5802700

5862649

5924806

5938220

5947132

5967714

5972386

5988359

5993229

6030524

6082961

6111997

6127999

6153120

6183647

6200045

6244872

6247010

6270036

6273442

6277250

6297153

6314453

6332862

6530491

6552993

6598058

6619817

6683563

6687560

6733409

A_44_P553037

A_44_P591761

A_64_P016190

GE1156955

GO:0001938

GO:0002376

GO:0005524

GO:0005764

GO:0005783

GO:0005886

GO:0006629

GO:0008270

GO:0008610

GO:0009792

GO:0010468

GO:0019901

GO:0030036

GO:0030335

GO:0030838

GO:0031929

GO:0031932

GO:0032008

GO:0032956

GO:0038203

GO:0043022

GO:0043491

GO:0043539

GO:0048856

GO:0050727

GO:0051896

GO:0051897

GO:0060090

GO:0098772

GO:0140767

GO:0140896

GO:0160049

GO:1902554

GO:2000114

ILMN_1359956

PH_rn_0005703

rc_AA893970_at

Participates

as a component of

mTORC2:PIP3 [plasma membrane] (Rattus norvegicus)

Inferred From

RICTOR [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_038959455.1

ENSEMBL

ENSRNOT00000109110, ENSRNOG00000011341, ENSRNOP00000079615

RGD

1307224