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EIF2AK2 [cytosol]
Stable Identifier
R-RNO-168699
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
Q63184
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Interferon Signaling (Rattus norvegicus)
Antiviral mechanism by IFN-stimulated genes (Rattus norvegicus)
ISG15 antiviral mechanism (Rattus norvegicus)
ISGylation of host proteins (Rattus norvegicus)
ISG15 targets [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
ISGylated host proteins [cytosol] (Rattus norvegicus)
ISG15 targets [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Rattus norvegicus)
ISG15 targets [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
ISGylated host proteins [cytosol] (Rattus norvegicus)
ISG15 targets [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
PKR-mediated signaling (Rattus norvegicus)
ADAR1 binds PKR (Rattus norvegicus)
ADAR1 dimer:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
DNAJC3 binds PKR (Rattus norvegicus)
DNAJC3:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
DUS2 binds PKR (Rattus norvegicus)
DUS2:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
FA core complex:HSP70s binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
Heparin binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 dimer:heparin [cytosol] (Rattus norvegicus)
EIF2AK2 dimer [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
IKK complex is activated by PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
ILF3 binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
ILF3:EIF2AK2 dimer [cytosol] (Rattus norvegicus)
EIF2AK2 dimer [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
ISGylation of PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
NCK1 binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2:NCK1 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
NPM binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
NPM1:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
PKR binds activating host RNA (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 dimer:Host RNA activators [cytosol] (Rattus norvegicus)
EIF2AK2 dimer [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
PKR inhibitors bind PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2:PKR inhibitors [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
SPHK1 binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2:p-SPHK1 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
STAT1,STAT3 binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
STAT1,STAT3:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
p-PRKRA dimer binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
p-TARBP2 binds PKR (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
p-TARBP2:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q63184
Reference Genes
BioGPS Gene:54287
ENSEMBL:ENSRNOG00000048315
ENSEMBL:ENSRNOG00055022558
ENSEMBL:ENSRNOG00060013534
KEGG:rno:54287
Monarch:54287
NCBI Gene:54287
UCSC:Q63184
Reference Transcript
RefSeq:NM_019335.1
Participates
as a member of
ISG15 targets [cytosol] (Rattus norvegicus)
as an input of
ADAR1 binds PKR (Rattus norvegicus)
DUS2 binds PKR (Rattus norvegicus)
SPHK1 binds PKR (Rattus norvegicus)
DNAJC3 binds PKR (Rattus norvegicus)
Heparin binds PKR (Rattus norvegicus)
PKR binds activating host RNA (Rattus norvegicus)
STAT1,STAT3 binds PKR (Rattus norvegicus)
NCK1 binds PKR (Rattus norvegicus)
ISGylation of PKR (Rattus norvegicus)
ILF3 binds PKR (Rattus norvegicus)
NPM binds PKR (Rattus norvegicus)
p-PRKRA dimer binds PKR (Rattus norvegicus)
PKR inhibitors bind PKR (Rattus norvegicus)
p-TARBP2 binds PKR (Rattus norvegicus)
FA core complex:HSP70s binds PKR (Rattus norvegicus)
IKK complex is activated by PKR (Rattus norvegicus)
as a component of
p-TARBP2:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2:PKR inhibitors [cytosol] (Rattus norvegicus)
ADAR1 dimer:EIF2AK2 [cytosol] (Rattus norvegicus)
DNAJC3:EIF2AK2 [cytosol] (Rattus norvegicus)
DUS2:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2:NCK1 [cytosol] (Rattus norvegicus)
EIF2AK2:p-SPHK1 [cytosol] (Rattus norvegicus)
STAT1,STAT3:EIF2AK2 [cytosol] (Rattus norvegicus)
NPM1:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2 dimer [cytosol] (Rattus norvegicus)
FA Core Complex:HSP70s:EIF2AK2 [cytosol] (Rattus norvegicus)
EIF2AK2:CHUK:IKBKB:IKBKG [cytosol] (Rattus norvegicus)
Other forms of this molecule
SUMO-EIF2AK2 [cytosol]
ISG15-EIF2AK2 [cytosol]
phospho-p-EIF2AK2 [cytosol]
phospho-p-EIF2AK2 [nucleoplasm]
Inferred From
EIF2AK2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_062208.1
PRO
Q63184
RGD
3402
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