Reactome | Atp6v1h [cytosol]

Atp6v1h [cytosol]

Stable Identifier

R-RNO-167578

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

ATP6V1H, A0A8I5ZWI2

Locations in the PathwayBrowser

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Cellular responses to stimuli (Rattus norvegicus)

- Cellular responses to stress (Rattus norvegicus)
  - Cellular response to starvation (Rattus norvegicus)
    - Amino acids regulate mTORC1 (Rattus norvegicus)
      - RRAGA,B exchanges GDP for GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - RRAGA,B hydrolyzes GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - RRAGC,D exchanges GTP for GDP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - RRAGC,D hydrolyzes GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - mTORC1 binds RHEB:GTP (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Rattus norvegicus)
        
        v-ATPase [lysosomal membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by Insulin receptor (Rattus norvegicus)
    - Insulin receptor recycling (Rattus norvegicus)
      - ATP6AP1 binds V-ATPase (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)
      - Endosome acidification (Rattus norvegicus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Rattus norvegicus)
        
        V-ATPase [endosome membrane] (Rattus norvegicus)
        
        ATP6V1 [cytosol] (Rattus norvegicus)
        
        Atp6v1h [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5ZWI2

Gene Names

Atp6v1h

Reference Genes

ENSEMBL:ENSRNOG00000030862

ENSEMBL:ENSRNOG00000030862.6 Atp6v1h

Other Identifiers

10875218

17805548

297797

5658476

5687803

5693295

5831413

5853190

5973044

6094825

6182228

6213427

6236769

6244758

6296348

6390023

6489471

6623382

6679703

6681297

6687908

6744285

A_42_P455802

A_44_P159296

GE12775

GO:0000221

GO:0005215

GO:0005773

GO:0006897

GO:0016020

GO:0016192

GO:0033176

GO:0043226

GO:0046961

GO:0055085

GO:0097401

GO:0140657

GO:1902495

GO:1902600

rc_AA942681_at

Participates

as a component of

ATP6V1 [cytosol] (Rattus norvegicus)

Inferred From

ATP6V1H [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOP00000083793, ENSRNOT00000104841, ENSRNOG00000030862

RGD

1562450

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