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Cell surface:C4b:C2a [plasma membrane]
Stable Identifier
R-RNO-166784
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Complement cascade (Rattus norvegicus)
Activation of C3 and C5 (Rattus norvegicus)
Activation of C5 (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cleavage of C3 by C3 convertases (Rattus norvegicus)
C3 convertases [plasma membrane] (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Formation of classic pathway C5 convertase (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Initial triggering of complement (Rattus norvegicus)
Formation of Classical C3 convertase (C4b:C2a complex) (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Regulation of Complement cascade (Rattus norvegicus)
CD55 (DAF) binds C3bBb, C4bC2a (Rattus norvegicus)
CD55:C4bC2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
CR1 binds C3bBb/C4bC2a (Rattus norvegicus)
CR1:C4bC2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
C2 [extracellular region]
(Rattus norvegicus)
Cell surface:C4b [plasma membrane]
(Rattus norvegicus)
Participates
as a component of
C4 binding protein:C4bC2a [plasma membrane] (Rattus norvegicus)
CD55:C4bC2a [plasma membrane] (Rattus norvegicus)
CR1:C4bC2a [plasma membrane] (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
as an input of
CD55 (DAF) binds C3bBb, C4bC2a (Rattus norvegicus)
CR1 binds C3bBb/C4bC2a (Rattus norvegicus)
Formation of classic pathway C5 convertase (Rattus norvegicus)
as an output of
Formation of Classical C3 convertase (C4b:C2a complex) (Rattus norvegicus)
as a member of
C3 convertases [plasma membrane] (Rattus norvegicus)
Inferred From
C4bC2a, C3bBb [plasma membrane]
(Homo sapiens)
Cell surface:C4b:C2a [plasma membrane]
(Homo sapiens)
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