Reactome | Mbl2 [extracellular region]

Mbl2 [extracellular region]

Stable Identifier

R-RNO-166674

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

extracellular region

Synonyms

MBL2, P08661

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Innate Immune System (Rattus norvegicus)
  - Complement cascade (Rattus norvegicus)
    - Initial triggering of complement (Rattus norvegicus)
      - Conversion of C2 into C2a and C2b (Rattus norvegicus)
        
        C4 activators [plasma membrane] (Rattus norvegicus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Rattus norvegicus)
        
        MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Rattus norvegicus)
        
        MBL2 dodecamer [extracellular region] (Rattus norvegicus)
        
        MBL2 trimer [extracellular region] (Rattus norvegicus)
        
        Mbl2 [extracellular region] (Rattus norvegicus)
      - Conversion of C4 into C4a and C4b (Rattus norvegicus)
        
        C4 activators [plasma membrane] (Rattus norvegicus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Rattus norvegicus)
        
        MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Rattus norvegicus)
        
        MBL2 dodecamer [extracellular region] (Rattus norvegicus)
        
        MBL2 trimer [extracellular region] (Rattus norvegicus)
        
        Mbl2 [extracellular region] (Rattus norvegicus)
      - Creation of C4 and C2 activators (Rattus norvegicus)
        
        Lectin pathway of complement activation (Rattus norvegicus)
        
        Activation of MASPs (Rattus norvegicus)
        
        MBL2,FCN:MASPs:carbohydrate patterns [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:MASP1 dimer:MASP2-1 dimer:Bacterial mannose surface pattern:4xCa2+ [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Rattus norvegicus)
        
        MBL2 dodecamer [extracellular region] (Rattus norvegicus)
        
        MBL2 trimer [extracellular region] (Rattus norvegicus)
        
        Mbl2 [extracellular region] (Rattus norvegicus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Rattus norvegicus)
        
        MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Rattus norvegicus)
        
        MBL2 dodecamer [extracellular region] (Rattus norvegicus)
        
        MBL2 trimer [extracellular region] (Rattus norvegicus)
        
        Mbl2 [extracellular region] (Rattus norvegicus)
        
        MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Rattus norvegicus)
        
        MBL2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Rattus norvegicus)
        
        MBL2 dodecamer [extracellular region] (Rattus norvegicus)
        
        MBL2 trimer [extracellular region] (Rattus norvegicus)
        
        Mbl2 [extracellular region] (Rattus norvegicus)
        
        MBL2 dodecamer:MASP1 dimer:MASP2-1 dimer:Bacterial mannose surface pattern:4xCa2+ [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Rattus norvegicus)
        
        MBL2 dodecamer [extracellular region] (Rattus norvegicus)
        
        MBL2 trimer [extracellular region] (Rattus norvegicus)
        
        Mbl2 [extracellular region] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P08661

Gene Names

Mbl2

Reference Genes

BioGPS Gene:64668 Mbl2

ENSEMBL:ENSRNOG00000050305

KEGG Gene (Rattus norvegicus):64668 Mbl2

Monarch:64668 Mbl2

NCBI Gene:64668 Mbl2

UCSC:P08661 Mbl2

Reference Transcript

Participates

as a component of

MBL2 trimer [extracellular region] (Rattus norvegicus)

Inferred From

MBL2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_003749136.1, XP_003749135.1, XP_006231311.1, XP_006231312.1, NP_073195.2

PRO

P08661

RGD

67380

PDB

1RDO, 1RDK, 1KZD, 1RDJ, 1RDN, 1KZC, 1RDM, 1RDI, 1BV4, 1KZB, 1RDL, 1KZA, 1KZE