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RFC Heteropentamer [nucleoplasm]
Stable Identifier
R-PFA-68436
Type
Complex
Species
Plasmodium falciparum
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Plasmodium falciparum)
Cell Cycle, Mitotic (Plasmodium falciparum)
S Phase (Plasmodium falciparum)
Synthesis of DNA (Plasmodium falciparum)
DNA strand elongation (Plasmodium falciparum)
Lagging Strand Synthesis (Plasmodium falciparum)
Polymerase switching (Plasmodium falciparum)
Loading of PCNA - Sliding Clamp Formation (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC binding displaces Pol Alpha (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC dissociates after sliding clamp formation (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
Leading Strand Synthesis (Plasmodium falciparum)
Polymerase switching (Plasmodium falciparum)
Loading of PCNA - Sliding Clamp Formation (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC binding displaces Pol Alpha (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC dissociates after sliding clamp formation (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
DNA Repair (Plasmodium falciparum)
DNA Damage Bypass (Plasmodium falciparum)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Plasmodium falciparum)
Translesion Synthesis by POLH (Plasmodium falciparum)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Plasmodium falciparum)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Plasmodium falciparum)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Plasmodium falciparum)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Plasmodium falciparum)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
Translesion synthesis by POLI (Plasmodium falciparum)
POLI incorporates dNMP opposite to damaged DNA base (Plasmodium falciparum)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
Translesion synthesis by POLK (Plasmodium falciparum)
POLK incorporates dNMP opposite to damaged DNA base (Plasmodium falciparum)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
Translesion synthesis by REV1 (Plasmodium falciparum)
POLZ extends translesion synthesis (Plasmodium falciparum)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Plasmodium falciparum)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
REV1 binds AP-dsDNA (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
REV1 inserts dCMP opposite to AP sites in DNA (Plasmodium falciparum)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Plasmodium falciparum)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Plasmodium falciparum)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
Nucleotide Excision Repair (Plasmodium falciparum)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Plasmodium falciparum)
Dual incision in TC-NER (Plasmodium falciparum)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
Gap-filling DNA repair synthesis and ligation in TC-NER (Plasmodium falciparum)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Plasmodium falciparum)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
DNA Replication (Plasmodium falciparum)
Synthesis of DNA (Plasmodium falciparum)
DNA strand elongation (Plasmodium falciparum)
Lagging Strand Synthesis (Plasmodium falciparum)
Polymerase switching (Plasmodium falciparum)
Loading of PCNA - Sliding Clamp Formation (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC binding displaces Pol Alpha (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC dissociates after sliding clamp formation (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
Leading Strand Synthesis (Plasmodium falciparum)
Polymerase switching (Plasmodium falciparum)
Loading of PCNA - Sliding Clamp Formation (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC binding displaces Pol Alpha (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC dissociates after sliding clamp formation (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer [nucleoplasm] (Plasmodium falciparum)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
RFC1 [nucleoplasm]
(Plasmodium falciparum)
RFC2 [nucleoplasm]
(Plasmodium falciparum)
RFC3 [nucleoplasm]
(Plasmodium falciparum)
RFC4 [nucleoplasm]
(Plasmodium falciparum)
RFC5 [nucleoplasm]
(Plasmodium falciparum)
Participates
as a component of
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Plasmodium falciparum)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Plasmodium falciparum)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Plasmodium falciparum)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Plasmodium falciparum)
as an input of
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Plasmodium falciparum)
RFC binding displaces Pol Alpha (Plasmodium falciparum)
as an output of
RFC dissociates after sliding clamp formation (Plasmodium falciparum)
Inferred From
RFC,(CFT18-RFC) [nucleoplasm]
(Homo sapiens)
RFC Heteropentamer [nucleoplasm]
(Homo sapiens)
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