Reactome | POLR2J [nucleoplasm]

POLR2J

Stable Identifier

R-PFA-63531

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

nucleoplasm

Synonyms

Q8IER7

Locations in the PathwayBrowser

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DNA Repair (Plasmodium falciparum)

- Nucleotide Excision Repair (Plasmodium falciparum)
  - Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Plasmodium falciparum)
    - Formation of TC-NER Pre-Incision Complex (Plasmodium falciparum)
      - Active RNA Pol II complex transcribes lesion-containing DNA template (Plasmodium falciparum)
        
        Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Plasmodium falciparum)
        
        RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Plasmodium falciparum)
        
        POLR2J [nucleoplasm] (Plasmodium falciparum)
        
        Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Plasmodium falciparum)
        
        RNA Polymerase II holoenzyme complex (hyperphosphorylated) [nucleoplasm] (Plasmodium falciparum)
        
        POLR2J [nucleoplasm] (Plasmodium falciparum)

Gene expression (Transcription) (Plasmodium falciparum)

- RNA Polymerase II Transcription (Plasmodium falciparum)
  - RNA Polymerase II Transcription Elongation (Plasmodium falciparum)
    - Formation of the Early Elongation Complex (Plasmodium falciparum)
      - DSIF complex binds to RNA Pol II (hypophosphorylated) (Plasmodium falciparum)
        
        RNA Pol II (hypophosphorylated) complex bound to DSIF protein [nucleoplasm] (Plasmodium falciparum)
        
        RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Plasmodium falciparum)
        
        RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Plasmodium falciparum)
        
        POLR2J [nucleoplasm] (Plasmodium falciparum)
        
        RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] (Plasmodium falciparum)
        
        RNA Polymerase II holoenzyme complex (hypophosphorylated):TFIIF complex [nucleoplasm] (Plasmodium falciparum)
        
        POLR2J [nucleoplasm] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:Q8IER7

Reference Genes

BioGPS Gene:814002

dbSNP Gene:814002

ENSEMBL:PF3D7_1304900

KEGG Glycan:pfa:PF13_0023

Monarch:814002

NCBI Gene:814002

PlasmoDB:PF3D7_1304900

Reference Transcript

RefSeq:XM_001349739.1

Participant Of

hasComponent

Inferred From

POLR2J [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_001349775.1

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