AGER binds rat ERK1/2

Stable Identifier
R-NUL-997411
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
General
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PNG
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 | PPTX  | SBGN
AGER binds rat ERK1/2
A membrane-proximal cytoplasmic region of the advanced glycation end-products receptor (AGER) is responsible for binding to extracellular signal-regulated protein kinase-1 and -2 (ERK1/2 or MAPK3/1). This region is similar to the D-domain, an ERK docking site which is conserved in some ERK substrates (Ishihara et al. 2003).
Literature References
PubMed ID Title Journal Year
12935895 The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site

Ishihara, K, Tsutsumi, K, Kawane, S, Nakajima, M, Kasaoka, T

FEBS Lett 2003
Participants
Input
Output
Orthologous Events
AGER binds ERK1/2 (Homo sapiens)
Authored
Jupe, S  (2010-06-17)
Reviewed
Yan, SD  (2010-11-09)
Created
Jupe, S  (2010-11-09)
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