Mutyh cleaves adenine mispaired with 8-oxoguanine

Stable Identifier
R-NUL-9635966
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Mutyh cleaves adenine mispaired with 8-oxoguanine

Wild-type mouse Mutyh removes adenine mispaired with 8-oxoguanine from damaged DNA (Yanaru-Fujisawa et al. 2008).

Literature References
PubMed ID Title Journal Year
18422726 Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis

Yanaru-Fujisawa, R, Matsumoto, T, Ushijima, Y, Esaki, M, Hirahashi, M, Gushima, M, Yao, T, Nakabeppu, Y, Iida, M

Clin. Genet. 2008
Participants
Catalyst Activity

DNA N-glycosylase activity of Mutyh:(OGUA:Ade)-dsDNA [nucleoplasm]

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