Ntrk3 phosphorylates Shc1

Stable Identifier
R-NUL-9036937
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ntrk3 phosphorylates Shc1
Recombinant rat Ntrk3 (TrkC), activated by recombinant human NTF3 (NT-3), phosphorylates mouse Shc1 on unknown tyrosine residue(s) (Yuen and Mobley 1999).
Literature References
PubMed ID Title Journal Year
10486198 Early BDNF, NT-3, and NT-4 signaling events

Yuen, EC, Mobley, WC

Exp. Neurol. 1999
Participants
Input
Output
Catalyst Activity

protein tyrosine kinase activity of NTF3:p-5Y-Ntrk3 homodimer:Shc1 [plasma membrane]

Physical Entity
NTF3:p-5Y-Ntrk3 homodimer:Shc1 [plasma membrane] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
Orthologous Events
NTRK3 phosphorylates SHC1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-01-02)
Reviewed
Tsoulfas, P  (2018-05-09)
Created
Orlic-Milacic, M  (2018-02-14)
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