Reactome | Ring1 [nucleoplasm]

Ring1 [nucleoplasm]

Stable Identifier

R-MMU-9977997

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

E3 ubiquitin-protein ligase RING1 ecNumber: 2.3.2.27, RING1_MOUSE

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - PTEN Regulation (Mus musculus)
      - Regulation of PTEN gene transcription (Mus musculus)
        
        MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Mus musculus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Mus musculus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Mus musculus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        RING1,RNF2 [nucleoplasm] (Mus musculus)
        
        Ring1 [nucleoplasm] (Mus musculus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        RING1,RNF2 [nucleoplasm] (Mus musculus)
        
        Ring1 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:O35730 Ring1

Gene Names

Ring1, Ring1A, Rnf1

Chain

chain:1-406

Reference Genes

BioGPS Gene:19763 Ring1

KEGG:mmu:19763 Ring1

Monarch:19763 Ring1

NCBI Gene:19763 Ring1

UCSC:O35730 Ring1

Reference Transcript

RefSeq:NM_009066.3 Ring1

Other Identifiers

103236_at

10450089

1422647_at

17343724

19763

4415476

4493806

4522959

4575455

4591048

4684328

4795744

4965398

5107873

5140980

5214001

5259040

5513773

5603157

A_51_P455266

A_52_P41728

GE33574

GO:0000151

GO:0001739

GO:0003682

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0006325

GO:0006338

GO:0006355

GO:0008270

GO:0009952

GO:0016567

GO:0016604

GO:0016607

GO:0016740

GO:0031519

GO:0035102

GO:0045892

GO:0046872

GO:0048593

GO:0061630

GO:0097027

GO:0098772

GO:0140096

ILMN_2770715

mMC005150

Participates

as a component of

as a member of

Inferred From

RING1 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSG00000024325, ENSMUST00000025183, ENSMUSP00000025183

IntEnz

2.3.2.27

PRO

O35730

MGI

1101770

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P23798 Pcgf2	2	Pcgf2 [nucleoplasm] (R-MMU-5619463) Pcgf2 [nucleoplasm] (R-MMU-389115)	0.527	3

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