Reactome | Rps10 [cytosol]

Rps10 [cytosol]

Stable Identifier

R-MMU-9948298

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

K63polyUb-K138,K139-RPS10, P63325

Locations in the PathwayBrowser

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Metabolism of proteins (Mus musculus)

- Translation (Mus musculus)
  - Ribosome-associated quality control (Mus musculus)
    - ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA (Mus musculus)
      - RQT complex binds K63polyUb-80S ribosome:no-go mRNA:peptidyl-tRNA with nascent peptide (Mus musculus)
        
        K63polyUb-80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Mus musculus)
        
        K63polyUb-80S ribosome [cytosol] (Mus musculus)
        
        K63polyUb-40S ribosomal subunit [cytosol] (Mus musculus)
        
        Rps10 [cytosol] (Mus musculus)
        
        RQT complex:K63polyUb-80S Ribosome:no-go mRNA:peptidyl tRNA with nascent peptide [cytosol] (Mus musculus)
        
        K63polyUb-80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Mus musculus)
        
        K63polyUb-80S ribosome [cytosol] (Mus musculus)
        
        K63polyUb-40S ribosomal subunit [cytosol] (Mus musculus)
        
        Rps10 [cytosol] (Mus musculus)
      - ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit (Mus musculus)
        
        K63polyUb-80S Ribosome:no-go mRNA:peptidyl-tRNA with elongating peptide [cytosol] (Mus musculus)
        
        K63polyUb-80S ribosome [cytosol] (Mus musculus)
        
        K63polyUb-40S ribosomal subunit [cytosol] (Mus musculus)
        
        Rps10 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:P63325 Rps10

Gene Names

Rps10

Chain

chain:1-165

Reference Genes

BioGPS Gene:67097 Rps10

KEGG:mmu:67097 Rps10

Monarch:67097 Rps10

NCBI Gene:67097 Rps10

UCSC:P63325 Rps10

Reference Transcript

RefSeq:NM_025963.4 Rps10

Other Identifiers

10438564

10449370

10494296

1416719_a_at

1434854_a_at

1436384_at

1438723_a_at

1439374_x_at

1456497_x_at

17342761

4339180

4422274

4457523

4559996

4616356

4719566

4743728

4773307

4818536

4847729

4867092

5009679

5204845

5300060

5313502

5338703

5418390

5440145

5443892

5445063

5446672

5465194

5467452

67097

99093_at

A_51_P169156

A_55_P2051047

A_66_P140711

GE41463

GO:0000028

GO:0000049

GO:0002181

GO:0003723

GO:0003735

GO:0005198

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0022626

GO:0022627

GO:0045202

GO:0065003

GO:0098793

GO:0098794

GO:0140236

GO:0140242

GO:1990904

ILMN_2743173

ILMN_2897617

mMC021027

Participates

as a component of

K63polyUb-40S ribosomal subunit [cytosol] (Mus musculus)

Other forms of this molecule

Rps10 [nucleoplasm]

Rps10 [cytosol]

Inferred From

K63polyUb-K138,K139-RPS10 [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (K63polyUb [cytosol]) at 138 (in Homo sapiens)

Coordinate

138

Modification

K63polyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Name

ubiquitinylated lysine (K63polyUb [cytosol]) at 139 (in Homo sapiens)

Coordinate

139

Modification

K63polyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_080239.1

ENSEMBL

ENSMUSP00000136042, ENSMUST00000114882, ENSMUSP00000110532, ENSMUSP00000110531, ENSMUSG00000052146, ENSMUST00000114881, ENSMUST00000178774

PRO

P63325

MGI

1914347

PDB

7CPU, 7LS1, 7LS2, 7CPV