Reactome | N4bp1 [cytosol]

N4bp1 [cytosol]

Stable Identifier

R-MMU-9757940

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

N4BP1(1-424), Q6A037

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Signaling by Interleukins (Mus musculus)
    - Interleukin-1 family signaling (Mus musculus)
      - Interleukin-1 signaling (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
- Innate Immune System (Mus musculus)
  - Toll-like Receptor Cascades (Mus musculus)
    - Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
      - MyD88 cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
    - Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
      - Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
      - Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
    - Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
      - TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
    - Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
      - MyD88-independent TLR4 cascade (Mus musculus)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
    - Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
      - MyD88 cascade initiated on plasma membrane (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
      - MyD88 dependent cascade initiated on endosome (Mus musculus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)
    - Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
      - MyD88 dependent cascade initiated on endosome (Mus musculus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
        
        TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
        
        Regulation of NF-kappa B signaling (Mus musculus)
        
        CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)
        
        N4bp1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q6A037

Gene Names

N4bp1

Reference Genes

BioGPS Gene:80750 N4bp1

ENSEMBL:ENSMUSG00000031652

KEGG:mmu:80750 N4bp1

Monarch:80750 N4bp1

NCBI Gene:80750 N4bp1

UCSC:Q6A037 N4bp1

Reference Transcript

RefSeq:NM_030563.2 N4bp1

Other Identifiers

103930_at

10580457

109950_at

111704_at

1418154_at

1446957_s_at

1455606_at

17511453

4414104

4425078

4534227

4596647

4611032

4624627

4703052

4818057

4946780

5049063

5088637

5091139

5159719

5182296

5347634

5380949

5443668

5563588

5603660

80750

A_51_P199788

A_52_P420216

GE41035

GO:0001818

GO:0002376

GO:0003723

GO:0003729

GO:0003824

GO:0004518

GO:0004540

GO:0005515

GO:0005634

GO:0005730

GO:0005737

GO:0005829

GO:0016605

GO:0016787

GO:0031397

GO:0032435

GO:0034644

GO:0043130

GO:0045071

GO:0045087

GO:0045088

GO:0098542

GO:0140098

ILMN_1239821

ILMN_2570913

ILMN_2621901

c81621_rc_at

mMC013493

Participates

as an output of

CASP8 cleaves N4BP1 at D424, D490 (Mus musculus)

Other forms of this molecule

N4bp1 [cytosol]

Inferred From

N4BP1(1-424), N4BP1(1-490) [cytosol] (Homo sapiens)

N4BP1(1-424) [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_085040.2

ENSEMBL

ENSMUSP00000034074, ENSMUSG00000031652, ENSMUST00000034074

PRO

Q6A037

MGI

2136825

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