Reactome | KCNJ4 [plasma membrane]

KCNJ4 [plasma membrane]

Stable Identifier

R-MMU-975336

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

P52189

Locations in the PathwayBrowser

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Neuronal System (Mus musculus)

- Potassium Channels (Mus musculus)
  - Inwardly rectifying K+ channels (Mus musculus)
    - Classical Kir channels (Mus musculus)
      - KCNJs transport K+ from the extracellular region to cytosol (Mus musculus)
        
        KCNJ tetramer [plasma membrane] (Mus musculus)
        
        KCNJs [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
    - G protein gated Potassium channels (Mus musculus)
      - Activation of G protein gated Potassium channels (Mus musculus)
        
        Activation of GIRK/Kir3 Channels (Mus musculus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Mus musculus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
- Transmission across Chemical Synapses (Mus musculus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Mus musculus)
    - GABA receptor activation (Mus musculus)
      - GABA B receptor activation (Mus musculus)
        
        Activation of GABAB receptors (Mus musculus)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Mus musculus)
        
        Activation of GIRK/Kir3 Channels (Mus musculus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Mus musculus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)
        
        Kir heterotetramers [plasma membrane] (Mus musculus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Mus musculus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Mus musculus)
        
        KCNJ4 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P52189

Reference Genes

ENSEMBL:ENSMUSG00000044216

Participant Of

hasMember

Inferred From

KCNJ4 [plasma membrane] (Homo sapiens)

Cross References

PRO

P52189

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62108 Dlg4	3	DLG4 [cytosol] (R-MMU-6794267) SAP-90 [plasma membrane] (R-MMU-443606) DLG4 [endocytic vesicle membrane] (R-MMU-416847)	0.527	3