Tbx5 and Kat5 bind the Srf gene

Stable Identifier
R-MMU-9735500
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
3/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Tbx5 and Kat5 bind the Srf gene
Tbx5 (Barron et al. 2005, He et al. 2011) and Kat5 (histone acetyltransferase TIP60, Barron et al. 2005) bind an enhancer in the 3' UTR of the Srf gene.
Literature References
PubMed ID Title Journal Year
21415370 Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

He, A, Kong, SW, Ma, Q, Pu, WT

Proc Natl Acad Sci U S A 2011
15591049 Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes

Barron, MR, Belaguli, NS, Zhang, SX, Trinh, M, Iyer, D, Merlo, X, Lough, JW, Parmacek, MS, Bruneau, BG, Schwartz, RJ

J Biol Chem 2005
Participants
Input
Output
Orthologous Events
TBX5 and KAT5 bind the SRF gene (Homo sapiens)
Authored
May, B  (2021-06-27)
Created
May, B  (2021-06-29)
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