Reactome | Atp6v0c [lysosomal membrane]

Atp6v0c [lysosomal membrane]

Stable Identifier

R-MMU-9640194

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

lysosomal membrane

Synonyms

ATP6V0C, P63082

Locations in the PathwayBrowser

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Cellular responses to stimuli (Mus musculus)

- Cellular responses to stress (Mus musculus)
  - Cellular response to starvation (Mus musculus)
    - Amino acids regulate mTORC1 (Mus musculus)
      - RRAGA,B exchanges GDP for GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
      - RRAGA,B hydrolyzes GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
      - RRAGC,D exchanges GTP for GDP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
      - RRAGC,D hydrolyzes GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
      - mTORC1 binds RHEB:GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0C hexamer [lysosomal membrane] (Mus musculus)
        
        Atp6v0c [lysosomal membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P63082

Gene Names

Atp6v0c

Reference Genes

BioGPS Gene:11984 Atp6v0c

ENSEMBL:ENSMUSG00000024121

KEGG:mmu:11984 Atp6v0c

Monarch:11984 Atp6v0c

NCBI Gene:11984 Atp6v0c

UCSC:P63082 Atp6v0c

Reference Transcript

Other Identifiers

10448455

10537316

10549653

11984

1416392_a_at

1435732_x_at

1438925_x_at

4380689

4404375

4435236

4436445

4460659

4464732

4530001

4541427

4627163

4711565

4715827

4727174

4736834

4786248

4857964

5052286

5056898

5100566

5149024

5171110

5306613

5324968

5378519

5502908

5516660

5548837

96919_at

A_52_P601240

A_55_P1979053

GE35100

GO:0000220

GO:0005515

GO:0005773

GO:0005774

GO:0006811

GO:0007035

GO:0007042

GO:0008553

GO:0015078

GO:0016020

GO:0016471

GO:0030177

GO:0030665

GO:0030672

GO:0031410

GO:0031625

GO:0033176

GO:0033177

GO:0033179

GO:0045202

GO:0046961

GO:0055085

GO:0097401

GO:0098588

GO:1902600

ILMN_1239946

ILMN_2518741

ILMN_2605556

m64298_s_at

mMC001126

mMC020000

Participates

as a component of

ATP6V0C hexamer [lysosomal membrane] (Mus musculus)

Other forms of this molecule

Atp6v0c [phagocytic vesicle membrane]

Atp6v0c [ficolin-1-rich granule membrane]

Atp6v0c [tertiary granule membrane]

Atp6v0c [plasma membrane]

Atp6v0c [azurophil granule membrane]

Atp6v0c [endosome membrane]

Inferred From

ATP6V0C [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_001348461.1, NP_033859.1

ENSEMBL

ENSMUST00000098862, ENSMUST00000024932, ENSMUSP00000024932, ENSMUSP00000111059, ENSMUSG00000024121

PRO

P63082

GlyGen

P63082

MGI

88116

PDB

9BRU, 9BRS, 9BRA, 9BRT, 9BRY, 9BRQ, 9BRZ, 9BRR

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