Reactome | Atp6v0e1 [lysosomal membrane]

Atp6v0e1 [lysosomal membrane]

Stable Identifier

R-MMU-9640180

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

lysosomal membrane

Synonyms

ATP6V0E1, Q9CQD8

Locations in the PathwayBrowser

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Cellular responses to stimuli (Mus musculus)

- Cellular responses to stress (Mus musculus)
  - Cellular response to starvation (Mus musculus)
    - Amino acids regulate mTORC1 (Mus musculus)
      - RRAGA,B exchanges GDP for GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
      - RRAGA,B hydrolyzes GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
      - RRAGC,D exchanges GTP for GDP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
      - RRAGC,D hydrolyzes GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
      - mTORC1 binds RHEB:GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V0 [lysosomal membrane] (Mus musculus)
        
        ATP6V0E [lysosomal membrane] (Mus musculus)
        
        Atp6v0e1 [lysosomal membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9CQD8

Gene Names

Atp6v0e1

Reference Genes

BioGPS Gene:11974 Atp6v0e1

CTD Gene:11974 Atp6v0e1

ENSEMBL:ENSMUSG00000015575

KEGG:mmu:11974 Atp6v0e1

Monarch:11974 Atp6v0e1

NCBI Gene:11974 Atp6v0e1

UCSC:Q9CQD8 Atp6v0e1

Reference Transcript

RefSeq:NM_025272.2 Atp6v0e1

Other Identifiers

10443021

11974

1416328_a_at

17334948

4475383

4527445

4685120

4698647

4710053

4719654

4913580

5028122

5114936

5277035

5422683

5550761

94301_at

AA590757_s_at

A_51_P336874

A_52_P178358

GE1430466

GE40646

GO:0006811

GO:0016020

GO:0033176

GO:0033179

GO:0046961

GO:0055085

GO:1902600

ILMN_2650911

mMC016402

Participates

as a member of

ATP6V0E [lysosomal membrane] (Mus musculus)

Other forms of this molecule

Atp6v0e1 [phagocytic vesicle membrane]

Atp6v0e1 [endosome membrane]

Inferred From

ATP6V0E1 [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_079548.1

ENSEMBL

ENSMUSP00000015719, ENSMUSG00000015575, ENSMUST00000167352, ENSMUST00000015719, ENSMUSP00000127552

PRO

Q9CQD8

GlyGen

Q9CQD8

MGI

1328318

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