Plins:Hspa8 binds Prkaa2

Stable Identifier
R-MMU-9613507
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Plins:Hspa8 binds Prkaa2

Lipophagy is the process of autophagic degradation of lipid droplets into fatty acids. Lipid droplets are coated with perilipin (Plin) protiens and they need to be eliminated for the degradation of the lipids inside. Cytosolic Heat shock cognate 71 kDa protein (Hspa8) binds Plin2 and Plin3 on the lipid droplet surface. Consequently, Prkaa2 bind and phosphorylate perilipins targeting them for lipophagy (S Kaushik et al. 2015, S Kaushik et al. 2016).

Literature References
Participants
Orthologous Events
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