Reactome | Dlg2 [plasma membrane]

Dlg2 [plasma membrane]

Stable Identifier

R-MMU-9610662

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

DLG2, Q91XM9

Locations in the PathwayBrowser

Expand all

Neuronal System (Mus musculus)

- Transmission across Chemical Synapses (Mus musculus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Mus musculus)
    - Activation of NMDA receptors and postsynaptic events (Mus musculus)
      - Unblocking of NMDA receptors, glutamate binding and activation (Mus musculus)
        
        Ca2+ influx into the post-synaptic cell (Mus musculus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Mus musculus)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Mus musculus)
        
        Dlg2 [plasma membrane] (Mus musculus)
        
        Membrane depolarization upon activation of Ca impermeable AMPA receptors (Mus musculus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Mus musculus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Mus musculus)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Mus musculus)
        
        Dlg2 [plasma membrane] (Mus musculus)

Signal Transduction (Mus musculus)

- MAPK family signaling cascades (Mus musculus)
  - MAPK1/MAPK3 signaling (Mus musculus)
    - RAF/MAP kinase cascade (Mus musculus)
      - RAS GEFs promote RAS nucleotide exchange (Mus musculus)
        
        RAS GEFs [plasma membrane] (Mus musculus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Mus musculus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Mus musculus)
        
        GRIN1:GRIN2B NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Mus musculus)
        
        DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Mus musculus)
        
        Dlg2 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q91XM9

Gene Names

Dlg2

Reference Genes

BioGPS Gene:23859 Dlg2

ENSEMBL:ENSMUSG00000052572

KEGG:mmu:23859 Dlg2

Monarch:23859 Dlg2

NCBI Gene:23859 Dlg2

UCSC:Q91XM9 Dlg2

Reference Transcript

Other Identifiers

10554900

109475_at

1421199_at

1421200_at

1437927_at

167045_at

17480143

23859

4315718

4332833

4358648

4384662

4435590

4480431

4525965

4555904

4579565

4602452

4609661

4618884

4640215

4662364

4669796

4675796

4682763

4688053

4692840

4696844

4730428

4764536

4782250

4794986

4814484

4820340

4856083

4862108

4868183

4882704

4901017

4904840

4920888

4931904

4935069

4977519

4982693

4994716

5024728

5036780

5039353

5041740

5050616

5055812

5129994

5155549

5257789

5266130

5276824

5319013

5320993

5363284

5370498

5412696

5422722

5430724

5438589

5441564

5475216

5500873

5506751

5526837

5537414

5562117

5569347

5569423

5589710

5617475

A_52_P1131821

A_52_P236484

A_52_P89049

A_55_P2072238

A_55_P2716371

A_55_P2716376

A_55_P2793723

A_66_P123709

A_66_P130703

GE33269

GO:0005198

GO:0005515

GO:0005886

GO:0007163

GO:0007268

GO:0007399

GO:0008076

GO:0014069

GO:0016020

GO:0016323

GO:0019233

GO:0019900

GO:0019901

GO:0030054

GO:0030424

GO:0030672

GO:0031594

GO:0035255

GO:0035418

GO:0035865

GO:0042995

GO:0043005

GO:0043113

GO:0043194

GO:0043204

GO:0043226

GO:0044224

GO:0045163

GO:0045197

GO:0045202

GO:0045211

GO:0048856

GO:0050877

GO:0061024

GO:0097120

GO:0098609

GO:0098839

GO:0098919

GO:0098978

GO:0099072

GO:0099562

GO:0099641

GO:0099642

GO:0099645

GO:1904115

ILMN_1220716

ILMN_1220778

ILMN_1253174

ILMN_2455560

ILMN_2518284

mMC001720

mMC020031

Participates

as a member of

DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Mus musculus)

Other forms of this molecule

Dlg2 [cytosol]

Inferred From

DLG2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001229976.1, NP_035937.2, XP_036008938.1, XP_036008927.1

ENSEMBL

ENSMUST00000107196, ENSMUSG00000052572, ENSMUSP00000102814, ENSMUSP00000158731, ENSMUST00000238619

PRO

Q91XM9

GlyGen

Q91XM9

MGI

1344351

PDB

2WL7

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62108 Dlg4	3	SAP-90 [plasma membrane] (R-MMU-443606) Dlg4 [endocytic vesicle membrane] (R-MMU-416847) Dlg4 [cytosol] (R-MMU-6794267)	0.623	6
UniProt:P35438 Grin1	3	Grin1 [plasma membrane] (R-MMU-3928395) Grin1 [endoplasmic reticulum membrane] (R-MMU-9610359) Grin1 [transport vesicle membrane] (R-MMU-9610566)	0.462	2

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