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Isg15 [cytosol]
Stable Identifier
R-MMU-936552
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
ISG15, Q64339
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Interferon Signaling (Mus musculus)
Antiviral mechanism by IFN-stimulated genes (Mus musculus)
ISG15 antiviral mechanism (Mus musculus)
Activation of ISG15 by UBA7 E1 ligase (Mus musculus)
ISG15:UBA7 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
Competitive inhibition of translation initiation by ISGylated 4EHP (Mus musculus)
ISGylated 4EHP [cytosol] (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylated 4EHP:mRNA [cytosol] (Mus musculus)
ISGylated 4EHP [cytosol] (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylation of E2 conjugating enzymes (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylated E2 conjugating enzymes [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylation of IRF3 (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylated IRF3 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylation of host protein filamin B (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylated Filamin B [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylation of host proteins (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylated host proteins [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylation of protein phosphatase 1 beta (PP2CB) (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylated PP2CB [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylation of protein translation regulator 4EHP (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISGylated 4EHP [cytosol] (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
Interaction of E3 ligase with ISG15:E2 complex (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Mus musculus)
ISG15:NEDD4 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Mus musculus)
ISGylated host proteins [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
Transfer of ISG15 from E1 to E2 (UBCH8) (Mus musculus)
ISG15:UBA7 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
PKR-mediated signaling (Mus musculus)
ISGylation of PKR (Mus musculus)
ISG15:UBCH8:ISG15 E3 ligase [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
Isg15 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q64339
Gene Names
Isg15
Reference Genes
BioGPS Gene:100038882 Isg15
ENSEMBL:ENSMUSG00000035692
ENSEMBL:ENSMUSG00000035692.8 Isg15
KEGG Gene (Mus musculus):100038882 Isg15
Monarch:100038882 Isg15
NCBI Gene:100038882 Isg15
UCSC:Q64339 Isg15
Reference Transcript
RefSeq:NM_015783.3 Isg15
Other Identifiers
100038882
10451287
1431591_s_at
17434023
4861678
5263912
5380311
98822_at
A_52_P463936
A_55_P2103698
GE36900
GO:0002376
GO:0005178
GO:0005515
GO:0005576
GO:0005737
GO:0007229
GO:0009615
GO:0009617
GO:0019941
GO:0023052
GO:0030154
GO:0030163
GO:0030501
GO:0031386
GO:0031397
GO:0031625
GO:0032020
GO:0032461
GO:0032649
GO:0032728
GO:0032729
GO:0032733
GO:0034340
GO:0036211
GO:0042742
GO:0045071
GO:0045087
GO:0045648
GO:0048856
GO:0051607
GO:0060339
GO:0065003
GO:0070585
GO:0098542
ILMN_1256257
mMC021626
x56602_s_at
Participates
as a component of
ISGylated PP2CB [cytosol] (Mus musculus)
ISGylated E2 conjugating enzymes [cytosol] (Mus musculus)
ISGylated Filamin B [cytosol] (Mus musculus)
ISG15:NEDD4 [cytosol] (Mus musculus)
ISGylated host proteins [cytosol] (Mus musculus)
ISG15:UBA7 [cytosol] (Mus musculus)
ISG15:UBCH8 [cytosol] (Mus musculus)
ISGylated IRF3 [cytosol] (Mus musculus)
as an input of
Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Mus musculus)
Activation of ISG15 by UBA7 E1 ligase (Mus musculus)
Other forms of this molecule
Isg15 [nucleoplasm]
Isg15 [nucleoplasm]
Inferred From
ISG15 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_056598.2
Ensembl
ENSMUSG00000035692
,
ENSMUSP00000082548
,
ENSMUST00000085425
PRO
Q64339
MGI
1855694
PDB
5CHV
,
5TL7
,
5TLA
,
5JZE
,
6J62
,
6YVA
,
5CHF
,
5CHW
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449621 REP
0.789
5
UniProt:Q9WTV6
1
Usp18 [cytosol]
(R-MMU-912325)
0.719
4
UniProt:P0C6U8-PRO_0000338257
0.618
3
UniProt:P0C6X7-PRO_0000037311 REP
0.558
4
UniProt:P0CG48 UBC
20
UBC(381-456) [endocytic vesicle membrane]
(R-HSA-939218)
UBC(533-608) [endocytic vesicle membrane]
(R-HSA-939220)
UBC(609-684) [endocytic vesicle membrane]
(R-HSA-939223)
UBC(457-532) [endocytic vesicle membrane]
(R-HSA-939195)
UBC(153-228) [endocytic vesicle membrane]
(R-HSA-939194)
UBC(305-380) [endocytic vesicle membrane]
(R-HSA-939228)
UBC(229-304) [endocytic vesicle membrane]
(R-HSA-939177)
UBC(77-152) [endocytic vesicle membrane]
(R-HSA-939210)
UBC(1-76) [endocytic vesicle membrane]
(R-HSA-939245)
Ub-565-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783166)
Ub-337-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783121)
Ub-185-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783154)
Ub-261-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783028)
Ub-413-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783061)
Ub-109-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783158)
Ub-641-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783182)
Ub-33-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783073)
Ub-489-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783078)
Ub-291-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783193)
Ub-595-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783130)
0.558
2
ChEBI:167176 GRL-0617
0.558
3
UniProt:K9N638-PRO_0000422456
0.558
2
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