Reactome | Atp6v1g1 [cytosol]

Atp6v1g1 [cytosol]

Stable Identifier

R-MMU-912578

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

ATP6V1G1, Q9CR51

Locations in the PathwayBrowser

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Cellular responses to stimuli (Mus musculus)

- Cellular responses to stress (Mus musculus)
  - Cellular response to starvation (Mus musculus)
    - Amino acids regulate mTORC1 (Mus musculus)
      - RRAGA,B exchanges GDP for GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - RRAGA,B hydrolyzes GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - RRAGC,D exchanges GTP for GDP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - RRAGC,D hydrolyzes GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - mTORC1 binds RHEB:GTP (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Mus musculus)
        
        v-ATPase:Ragulator [lysosomal membrane] (Mus musculus)
        
        v-ATPase [lysosomal membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)

Immune System (Mus musculus)

- Innate Immune System (Mus musculus)
  - ROS and RNS production in phagocytes (Mus musculus)
    - Intraphagosomal pH is lowered to 5 by V-ATPase (Mus musculus)
      - V-ATPase [phagocytic vesicle membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by Receptor Tyrosine Kinases (Mus musculus)
  - Signaling by Insulin receptor (Mus musculus)
    - Insulin receptor recycling (Mus musculus)
      - ATP6AP1 binds V-ATPase (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - Endosome acidification (Mus musculus)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)

Transport of small molecules (Mus musculus)

- Ion channel transport (Mus musculus)
  - ATP6AP1 binds V-ATPase (Mus musculus)
    - V-ATPase [endosome membrane] (Mus musculus)
      - ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
    - V-ATPase:ATP6AP1 [endosome membrane] (Mus musculus)
      - V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
- Iron uptake and transport (Mus musculus)
  - Transferrin endocytosis and recycling (Mus musculus)
    - ATP6AP1 binds V-ATPase (Mus musculus)
      - V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
      - V-ATPase:ATP6AP1 [endosome membrane] (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)
    - Acidification of Tf:TfR1 containing endosome (Mus musculus)
      - V-ATPase:ATP6AP1 [endosome membrane] (Mus musculus)
        
        V-ATPase [endosome membrane] (Mus musculus)
        
        ATP6V1 [cytosol] (Mus musculus)
        
        ATP6V1G dimer [cytosol] (Mus musculus)
        
        ATP6V1G [cytosol] (Mus musculus)
        
        Atp6v1g1 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9CR51

Gene Names

Atp6v1g1

Reference Genes

BioGPS Gene:66290 Atp6v1g1

ENSEMBL:ENSMUSG00000039105

KEGG:mmu:66290 Atp6v1g1

Monarch:66290 Atp6v1g1

NCBI Gene:66290 Atp6v1g1

UCSC:Q9CR51 Atp6v1g1

Reference Transcript

RefSeq:NM_024173.2 Atp6v1g1

Other Identifiers

10482330

10505461

1423255_at

1423256_a_at

1450926_at

17414760

4485511

4676107

4806203

4863245

5124730

5138489

5256697

5363832

5411813

66290

96281_at

A_51_P140171

A_52_P349738

A_55_P1988033

GE41881

GO:0000221

GO:0005515

GO:0005765

GO:0005829

GO:0005886

GO:0006811

GO:0006879

GO:0016020

GO:0016324

GO:0016471

GO:0016787

GO:0016887

GO:0033176

GO:0033180

GO:0036295

GO:0046961

GO:0051117

GO:0055085

GO:0097401

GO:0098793

GO:0098850

GO:1902600

GO:1904949

ILMN_1257673

ILMN_2928875

Msa.4924.0_s_at

aa615550_s_at

mMC019455

Participates

as a member of

ATP6V1G [cytosol] (Mus musculus)

Inferred From

ATP6V1G1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_077135.1

ENSEMBL

ENSMUSP00000048770, ENSMUSG00000039105, ENSMUST00000035301

PRO

Q9CR51

GlyGen

Q9CR51

MGI

1913540

HMDB Protein

HMDBP14075

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