Mecp2 binds Dll1 gene promoter

Stable Identifier
R-MMU-9023364
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Mecp2 binds Dll1 gene promoter

Mouse Mecp2 binds the promoter of the mouse Dll1 gene, encoding Notch ligand Delta 1. Binding of Mecp2 to the Dll1 gene promoter is inhibited by Aurkb-mediated phosphorylation of Mecp2 at serine residue S421 (Li et al. 2014).

Literature References
PubMed ID Title Journal Year
25420914 Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway

Li, H, Zhong, X, Chau, KF, Santistevan, NJ, Guo, W, Kong, G, Li, X, Kadakia, M, Masliah, J, Chi, J, Jin, P, Zhang, J, Zhao, X, Chang, Q

Nat Commun 2014
Participants
Orthologous Events
Authored
Reviewed
Created
Cite Us!