Mecp2 binds Gad1 gene promoter

Stable Identifier
R-MMU-9022931
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Mecp2 binds Gad1 gene promoter

Mouse Mecp2 binds the promoter region of the mouse Gad1 (Gad67) gene, encoding glutamate decarboxylase 1, an enzyme involved in GABA synthesis (Chao et al. 2010).

Literature References
PubMed ID Title Journal Year
21068835 Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Neul, JL, Chahrour, M, Xue, M, Samaco, RC, Noebels, JL, Zoghbi, HY, Rubenstein, JL, Chen, H, Lu, HC, Yoo, J, Ekker, M, Heintz, N, Rosenmund, C, Gong, S, Chao, HT

Nature 2010
Participants
Orthologous Events
Authored
Reviewed
Created
Cite Us!