Runx2 binds Hey1,Hey2,Hes1

Stable Identifier
R-MMU-9008180
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Runx2 binds Hey1,Hey2,Hes1
Mouse Runx2 forms complexes with protein products of Notch1 target genes Hey1, Hey2 or Hes1 (Garg et al. 2005, Hilton et al. 2008).
Literature References
PubMed ID Title Journal Year
16025100 Mutations in NOTCH1 cause aortic valve disease

Garg, V, Muth, AN, Ransom, JF, Schluterman, MK, Barnes, R, King, IN, Grossfeld, PD, Srivastava, D

Nature 2005
18297083 Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

Hilton, MJ, Tu, X, Wu, X, Bai, S, Zhao, H, Kobayashi, T, Kronenberg, HM, Teitelbaum, SL, Ross, FP, Kopan, R, Long, F

Nat. Med. 2008
Participants
Input
Output
Orthologous Events
RUNX2 binds HEY1,HEY2,HES1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-06-08)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2017-06-07)
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