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Ube2l3 [cytosol]
Stable Identifier
R-MMU-8864201
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Ub-C86-UBE2L3, P68037
Locations in the PathwayBrowser
Expand all
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
Selective autophagy (Mus musculus)
Mitophagy (Mus musculus)
PINK1-PRKN Mediated Mitophagy (Mus musculus)
PRKN ubiquitinates MOM substrates (Mus musculus)
Ub:Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Mus musculus)
Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Protein ubiquitination (Mus musculus)
E3 ubiquitin ligases ubiquitinate target proteins (Mus musculus)
RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Mus musculus)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
RNF144A polyubiquitinates PRKDC (Mus musculus)
RNF144A:PRKDC:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Mus musculus)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Mus musculus)
Ub:E2 (UBA1 substrate) [cytosol] (Mus musculus)
Ub-conjugated E2 enzyme (UBA1 substrate) [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Mus musculus)
Ub:E2 (UBA6 substrate) [cytosol] (Mus musculus)
Ub-conjugated E2 enzyme (UBA6 substrate) [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
ITCH polyubiquitinates MLKL at K50 (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
MLKL binds ITCH (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
p-S-RIPK1:p-S-RIPK3:p-T,S-MLKL:ITCH:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
PRKN polyubiquitinates RIPK3 (Mus musculus)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
RIPK3 binds p-S9-PRKN (Mus musculus)
RIPK3:p-S9-PRKN:Ub:UBE2L3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
LUBAC binds CFLAR (Mus musculus)
CFLAR:LUBAC:Ub:UBE2D3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
LUBAC ubiquitinates CFLAR at K351, K353 (Mus musculus)
CFLAR:LUBAC:Ub:UBE2D3 [cytosol] (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
LUBAC ubiquitinates RIPK1 at K627 (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Mus musculus)
Ub:UBE2L3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
Ube2l3 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:P68037
Gene Names
Ube2l3
Reference Genes
BioGPS Gene:22195 Ube2l3
ENSEMBL:ENSMUSG00000038965
KEGG:mmu:22195 Ube2l3
Monarch:22195 Ube2l3
NCBI Gene:22195 Ube2l3
UCSC:P68037 Ube2l3
Reference Transcript
RefSeq:NM_009456.3 Ube2l3
Other Identifiers
10362310
10438109
10458841
10499187
10502898
1417907_at
1417908_s_at
1448879_at
1448880_at
17328640
17548274
22195
4326012
4333056
4409108
4411884
4511078
4589081
4753233
4834365
4849985
4873469
4932677
4959363
5159806
5226106
5389206
5423140
5514578
5559599
97479_at
A_51_P196027
A_55_P2120278
A_55_P2125466
A_55_P2713325
A_55_P2848772
GE33857
GO:0000166
GO:0000209
GO:0003713
GO:0003824
GO:0004842
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0006355
GO:0006511
GO:0008283
GO:0016567
GO:0016740
GO:0019787
GO:0031398
GO:0031625
GO:0044770
GO:0045893
GO:0051603
GO:0061631
GO:0070979
GO:0071383
GO:0071385
GO:0097027
GO:0098772
GO:0140096
ILMN_2471793
ILMN_2475727
X97042_s_at
mMC010957
mMR031195
w78245_s_at
Participates
as a member of
Ub-conjugated E2 enzyme (UBA6 substrate) [cytosol] (Mus musculus)
Ub-conjugated E2 enzyme (UBA1 substrate) [cytosol] (Mus musculus)
Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Mus musculus)
as an output of
LUBAC ubiquitinates CFLAR at K351, K353 (Mus musculus)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Mus musculus)
LUBAC ubiquitinates RIPK1 at K627 (Mus musculus)
PRKN polyubiquitinates RIPK3 (Mus musculus)
ITCH polyubiquitinates MLKL at K50 (Mus musculus)
as a component of
Ub:UBE2L3 [cytosol] (Mus musculus)
Other forms of this molecule
Ube2l3 [nucleoplasm]
Ube2l3 [nucleoplasm]
Ube2l3 [cytosol]
Inferred From
Ub-C86-UBE2L3 [cytosol]
(Homo sapiens)
Modified Residues
Name
S-(glycyl)-L-cysteine (Cys-Gly) at 86 (in Homo sapiens)
Coordinate
86
PsiMod Name
S-(glycyl)-L-cysteine (Cys-Gly)
PsiMod Definition
A protein modification that effectively crosslinks an L-cysteine residue and a glycine residue by a thioester bond to form S-glycyl-L-cysteine.
Cross References
RefSeq
NP_033482.1
ENSEMBL
ENSMUSG00000038965
,
ENSMUSP00000156121
,
ENSMUST00000090192
,
ENSMUSP00000087658
,
ENSMUST00000232139
PRO
P68037
GlyGen
P68037
MGI
109240
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