Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Hpn [plasma membrane]
Stable Identifier
R-MMU-8849219
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
plasma membrane
Synonyms
HPN(163-417), O35453
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by MET (Mus musculus)
MET Receptor Activation (Mus musculus)
HPN heterodimer cleaves pro-HGF to form HGF dimer (Mus musculus)
HPN heterodimer [plasma membrane] (Mus musculus)
Hpn [plasma membrane] (Mus musculus)
Signaling by MST1 (Mus musculus)
HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Mus musculus)
HPN heterodimer [plasma membrane] (Mus musculus)
Hpn [plasma membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:O35453
Gene Names
Hpn
Reference Genes
BioGPS Gene:15451 Hpn
ENSEMBL:ENSMUSG00000001249
KEGG:mmu:15451 Hpn
Monarch:15451 Hpn
NCBI Gene:15451 Hpn
UCSC:O35453 Hpn
Reference Transcript
RefSeq:NM_001110252.2 Hpn
RefSeq:NM_008281.4 Hpn
RefSeq:NM_001276269.1 Hpn
Other Identifiers
10562234
1420712_a_at
15451
160639_at
17489441
4306690
4318895
4408071
4440700
4520282
4588949
4623460
4651607
4729620
4745615
4755306
4758618
4778963
4832046
4832865
4885175
4906505
4918892
4988556
5048121
5056162
5078882
5087934
5125132
5168275
5260315
5330150
5360551
5385724
5399096
5400316
5437565
5467662
5549604
5594554
AF030065_s_at
A_51_P434483
A_52_P83252
A_55_P1973583
GE42514
GO:0004252
GO:0005576
GO:0005737
GO:0005789
GO:0005886
GO:0005911
GO:0006508
GO:0007605
GO:0008233
GO:0008236
GO:0008360
GO:0009986
GO:0010628
GO:0010719
GO:0010756
GO:0016020
GO:0016324
GO:0016485
GO:0016787
GO:0030198
GO:0030307
GO:0031965
GO:0034769
GO:0042632
GO:0043025
GO:0043066
GO:0043923
GO:0048856
GO:0050680
GO:0050877
GO:0050910
GO:0055085
GO:0060429
GO:0065008
GO:0070008
GO:0071805
GO:0090103
GO:0097066
GO:0097195
GO:2000347
GO:2000611
ILMN_1221781
ILMN_1240252
ILMN_2969532
Msa.31790.0_s_at
Msa.5884.0_s_at
mMC008594
Participates
as a component of
HPN heterodimer [plasma membrane] (Mus musculus)
Other forms of this molecule
Hpn [plasma membrane]
Inferred From
HPN(163-417) [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001263198.1
,
NP_032307.2
,
NP_001103722.1
ENSEMBL
ENSMUSP00000103737
,
ENSMUSG00000001249
,
ENSMUST00000108102
PRO
O35453
GlyGen
O35453
MGI
1196620
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text